Evidence map›Paper›PMID 42115777›Full record

ArticleCommunications biology2026

MMP1 and PRSS23 induce PAR

Paulina D Ramírez-García, Igor Dolgalev, Zinaida Dubeykovskaya, Rocco Latorre, Leticia Arbex, Nguyen Huu Tu, Brian L Schmidt, Donna G Albertson

Abstract read
In one paragraph

Article in Communications biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Paulina D Ramírez-GarcíaTranslational Research Center, NYU Dentistry, New York, NY, USA.ORCID http://orcid.org/0000-0003-0971-3501
Igor DolgalevDepartment of Medicine, NYU Langone Health, New York, NY, USA.ORCID http://orcid.org/0000-0003-4451-126X
Zinaida DubeykovskayaTranslational Research Center, NYU Dentistry, New York, NY, USA.
Rocco LatorrePain Research Center, NYU Dentistry, New York, NY, USA.
Leticia ArbexTranslational Research Center, NYU Dentistry, New York, NY, USA.
Nguyen Huu TuTranslational Research Center, NYU Dentistry, New York, NY, USA.
Brian L SchmidtTranslational Research Center, NYU Dentistry, New York, NY, USA.ORCID http://orcid.org/0000-0002-2409-8984
Donna G AlbertsonTranslational Research Center, NYU Dentistry, New York, NY, USA. da66@nyu.edu.ORCID http://orcid.org/0000-0002-1433-6483

Funding

TRPV1 nociceptors in oral carcinogenesis and painR01CA231396 · NCI · NEW YORK UNIVERSITY · PI ALBERTSON, DONNA G, SCHMIDT, BRIAN L · 2021 to 2025
$3.1M
Artemin overexpression in oral cancer pain and carcinogenesisR01CA228525 · NCI · NEW YORK UNIVERSITY · PI ALBERTSON, DONNA G, SCHMIDT, BRIAN L · 2019 to 2024
$2.6M
Exploring PAR2 Trafficking in Oral Cancer: Implications for Pain Signaling and Drug DeliveryK99DE033792 · NIDCR · NEW YORK UNIVERSITY · PI RAMIREZ GARCIA, PAULINA DANIELA · 2024 to 2025
$271k
Center for Strategic Scientific Initiatives, National Cancer Institute (NCI Center for Strategic Scientific Initiatives) R01CA231396NCI NIH HHS R01 CA228525NCI NIH HHS R01 CA231396NIDCR NIH HHS K99 DE033792
6 · The paper itself

Abstract

Protease-activated receptor 2 (PAR

Indexed as

Cancer PainMatrix Metalloproteinase 1Mouth NeoplasmsReceptor, PAR-2Serine EndopeptidasesCell Line, TumorHumansSignal TransductionF2RL1 protein, humanMatrix Metalloproteinase 1MMP1 protein, humanReceptor, PAR-2Serine Endopeptidases

Identifiers

PMID42115777
PMCPMC13385804

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.