Evidence map›Paper›PMID 42115731›Full record

ArticleScientific reports2026

Multicenter retrospective analysis by the Polish Adult Leukemia Group on tuberculosis occurrence and outcomes after hematopoietic cell transplantation.

Joanna Drozd-Sokołowska, Anna Waszczuk-Gajda, Elżbieta Sienkiewicz, Agnieszka Piekarska, Łukasz Bołkun, Barbara Nasiłowska-Adamska, Magdalena Tormanowska, Joanna Kujawska, Małgorzata Sobczyk-Kruszelnicka, Paweł Szwedyk and 12 more

Abstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Joanna Drozd-SokołowskaDepartment of Hematology, Transplantation and Internal Medicine, Medical University of Warsaw, Banacha 1a Str., 02-097, Warsaw, Poland. Joanna.drozd-sokolowska@wum.edu.pl.
Anna Waszczuk-GajdaDepartment of Hematology, Transplantation and Internal Medicine, Medical University of Warsaw, Banacha 1a Str., 02-097, Warsaw, Poland.
Elżbieta SienkiewiczDepartment of Mathematics and Information Science, Warsaw University of Technology, Warsaw, Poland.
Agnieszka PiekarskaDepartment of Hematology and Transplantology, Medical University of Gdansk, Gdansk, Poland.
Łukasz BołkunDepartment of Hematology, Medical University of Bialystok, Bialystok, Poland.
Barbara Nasiłowska-AdamskaDepartment of Hematopoietic Stem Cell Transplantation, Institute of Hematology and Transfusion Medicine, Warsaw, Poland.
Magdalena TormanowskaDepartment of Hematopoietic Stem Cell Transplantation, Institute of Hematology and Transfusion Medicine, Warsaw, Poland.
Joanna KujawskaDepartment of Hematology and Bone Marrow Transplantation, Poznan University of Medical Sciences, Poznan, Poland.
Małgorzata Sobczyk-KruszelnickaMaria Sklodowska-Curie Institute-Cancer Center, Gliwice Branch, Gliwice, Poland.
Paweł SzwedykDepartment of Hematology, Ludwik Rydygier Hospital, Cracow, Poland.
Justyna RybkaDepartment of Hematology, Wroclaw Medical University, Wroclaw, Poland.
Joanna Romejko-JarosińskaMaria Sklodowska-Curie National Cancer Institute of Oncology, Warsaw, Poland.
Anna KopińskaDepartment of Hematology and Bone Marrow Transplantation, Medical University of Silesia, Katowice, Poland.
Mariola SędzimirskaLower Silesian Center for Cellular, Transplantation with National Bone Marrow Donor Registry, Wroclaw, Poland.
Izabela Dereń-WagemannLower Silesian Center for Cellular, Transplantation with National Bone Marrow Donor Registry, Wroclaw, Poland.
Jarosław DybkoLower Silesian Center for Cellular, Transplantation with National Bone Marrow Donor Registry, Wroclaw, Poland.
Małgorzata ProboszczDepartment of Internal Medicine, Pulmonary Diseases and Allergy, Medical University of Warsaw, Warsaw, Poland.
Agnieszka TomaszewskaDepartment of Hematology, Transplantation and Internal Medicine, Medical University of Warsaw, Banacha 1a Str., 02-097, Warsaw, Poland.
Przemysław BiecekDepartment of Mathematics and Information Science, Warsaw University of Technology, Warsaw, Poland.
Grzegorz BasakDepartment of Hematology, Transplantation and Internal Medicine, Medical University of Warsaw, Banacha 1a Str., 02-097, Warsaw, Poland.
Sebastian GiebelMaria Sklodowska-Curie Institute-Cancer Center, Gliwice Branch, Gliwice, Poland.
Lidia GilDepartment of Hematology and Bone Marrow Transplantation, Poznan University of Medical Sciences, Poznan, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tuberculosis (TB) is an infectious complication of hematopoietic cell transplantation (HCT). There is a paucity of data on TB after HCT. Here we present the data from a low/low-intermediate TB-burden country. This was a Retrospective analysis of adult patients who developed TB after HCT. Seventeen patients were identified, 9 (52.9%) females, the median age at TB 44 years. Five (29.4%) patients underwent auto-HCT, 12 (70.6%) allo-HCT, translating into the relative frequency of TB of 0.171% for allo-HCT, and 0.063% for auto-HCT. The median time from HCT to TB was 431 days (range, 5-973). All patients had pulmonary TB. Bacteriologically confirmed TB was diagnosed in 13 (76.5%) patients; drug susceptibility testing was performed in 3/13 (23.1%). The median duration of treatment was 6 months. Twelve out of 13 evaluable patients (92.3%) obtained treatment success. With a median follow-up of 48 months (95%CI 19-95) 1-year cumulative incidence of TB-associated death was 6.7% (95%CI 0.9-40.8%). To conclude TB is a very rare infectious complication of HCT. Most frequently TB develops late after HCT. The primary site involved is the lung with no extrapulmonary TB identified in the current analysis. TB can still result in the death of the affected patient.

Indexed as

Hematopoietic Stem Cell TransplantationLeukemiaTuberculosisAdultAgedAntitubercular AgentsFemaleHumansIncidenceMaleMiddle AgedPolandRetrospective StudiesTreatment OutcomeYoung AdultAntitubercular AgentsAnti-tuberculosis treatmentDrug-refractory tuberculosisHematopoietic cell transplantationMycobacterium tuberculosisTuberculosis

Identifiers

PMID42115731
PMCPMC13350841

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