Evidence map›Paper›PMID 42115565›Full record

ArticleInternal and emergency medicine2026

Diagnostic uncertainties in older inpatients with suspected heart failure with preserved ejection fraction: a pilot cohort study.

Roberto Presta, Enrico Brunetti, Francesco Palmas, Simone Carlone, Clara Musarò, Elena Cane, Marco Milan, Guido Sergio Giorgio Maggiani, Gianluca Isaia, Angela Sciacqua and 1 more

Abstract read
PubMed Publisher
In one paragraph

Article in Internal and emergency medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. HFpEF overclassification in older adults.Internal and emergency medicine · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Roberto PrestaSection of Geriatrics, City of Health and Science University Hospital, C.so Bramante, 88/90, 10126, Turin, Italy.ORCID http://orcid.org/0000-0001-6680-7681
Enrico BrunettiSection of Geriatrics, City of Health and Science University Hospital, C.so Bramante, 88/90, 10126, Turin, Italy. dott.brunettienrico@gmail.com.ORCID http://orcid.org/0000-0003-2028-2319
Francesco PalmasDepartment of Medical Sciences, University of Turin, Turin, Italy.
Simone CarloneDepartment of Medical Sciences, University of Turin, Turin, Italy.
Clara MusaròDepartment of Medical Sciences, University of Turin, Turin, Italy.
Elena CaneDepartment of Medical Sciences, University of Turin, Turin, Italy.
Marco MilanDepartment of Medical Sciences, University of Turin, Turin, Italy.
Guido Sergio Giorgio MaggianiSection of Geriatrics, City of Health and Science University Hospital, C.so Bramante, 88/90, 10126, Turin, Italy.ORCID http://orcid.org/0000-0003-0688-7063
Gianluca IsaiaSection of Geriatrics, City of Health and Science University Hospital, C.so Bramante, 88/90, 10126, Turin, Italy.ORCID http://orcid.org/0000-0002-0249-9170
Angela SciacquaDepartment of Medical and Surgical Sciences, University "Magna Græcia" of Catanzaro, Catanzaro, Italy.ORCID http://orcid.org/0000-0003-1674-5317
Mario BoSection of Geriatrics, City of Health and Science University Hospital, C.so Bramante, 88/90, 10126, Turin, Italy.ORCID http://orcid.org/0000-0003-2945-0243

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Heart failure (HF) with preserved ejection fraction (HFpEF) is increasingly suspected in older adults. However, diagnosis remains challenging due to nonspecific symptoms, age-related structural cardiac changes, and confounding comorbidities. Reliability of algorithms developed in younger populations may be limited in this population. This prospective study enrolled inpatients aged > 75 years with at least one ESC-listed typical sign/symptom suggestive of HF and no prior HF diagnosis were evaluated for HFpEF using ESC 2021 criteria. Structural/functional transthoracic echocardiographic (TTE) abnormalities and age-adjusted NT-proBNP thresholds were recorded. Diagnostic accuracy of the H

Indexed as

Heart FailureStroke VolumeAgedAged, 80 and overCohort StudiesEchocardiographyFemaleHumansInpatientsMaleNatriuretic Peptide, BrainPeptide FragmentsPilot ProjectsProspective StudiesReproducibility of ResultsROC CurveNatriuretic Peptide, BrainPeptide Fragmentspro-brain natriuretic peptide (1-76)H2FPEFHeart failureHFA-PEFFHFpEFNT-proBNPOlder inpatients

Identifiers

PMID42115565

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.