ReviewAdvances and technical standards in neurosurgery2026
History of Treatment of Pineal Tumors.
Review in Advances and technical standards in neurosurgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Pineal gland for a long time aroused the interest of scholars' philosophical and religious current of thought.Its history started in China in 2697 BC and in the Indu culture it was considered the centre of spiritual forces or the centre of vital energy. Herophilus (325-280) studied the pineal gland with anatomical dissection and considered the gland as the valve that permitted the flow of the vital "pnuema."Descartes (1596-1650), a French philosopher, gave a great impulsion to the studies on the role of the pineal gland. The location of the soul in the pineal gland was again proposed as it acts in the control of the human body. The human intellectual soul was characterized by the immortality, the free will, and the reason that characterize the power of imagination, the intellectual elaboration, and the faculty of commemoration, respectively.Ahlborn and Rabl-Ruckhardt (1839-1906) showed the similarity between the nonmammalian pineal gland and the primary optic vesicles. The visual function of the pineal gland was reported also by Helena Blavatsky (1831-1891) and a new era for its role started.In 1958 the hormone of the gland, the melatonin, was discovered by Lerner. Successively it demonstrated a variability of the production of the hormone in function of the exposition to light or dark and the implication in the control of the circadian rhythm. The theory of function of the internal clock of the pineal and the control of the circadian rhythm of an organism began to take form.At the same time the classification of the pineal tumor started and the first surgical approaches were proposed. The development of anesthesiology and the surgical tools in the last years permitted to make surgery accessible for patients reducing the rate of sequels and mortality.To know the "history" of the pineal gland and of pineal tumors, treatment permits to understand the evolution and the development of ideas concerning the diagnosis and treatment of these rare tumors.
Indexed as
Identifiers
42115450What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.