Evidence map›Paper›PMID 42115210›Full record

ArticleScientific reports2026

Enhanced antibacterial activities of zirconia nanoparticles modified with yttrium oxide and alumina.

Sally Mazin Saad, Enas Muhi Hadi, Nehia Neama Hussein, Haydar M Al-Kuraishy, Muhammad Faheem Akhtar, Majid S Jabir, Hani A Ba-Awadh, Alaa B Ismael, Ayman A Swelum

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Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Sally Mazin SaadCollege of Applied Sciences, University of Technology, Baghdad, 10066, Iraq.
Enas Muhi HadiCollege of Applied Sciences, University of Technology, Baghdad, 10066, Iraq.
Nehia Neama HusseinCollege of Applied Sciences, University of Technology, Baghdad, 10066, Iraq.
Haydar M Al-KuraishyDepartment of Clinical Pharmacology and Medicine, College of Medicine, Mustansiriyah University, Baghdad, Iraq.
Muhammad Faheem AkhtarLiaocheng Research Institute of Donkey High-Efficiency Breeding and Ecological Feeding, Liaocheng University, Liaocheng, 252059, China.
Majid S JabirCollege of Applied Sciences, University of Technology, Baghdad, 10066, Iraq. 100131@uotechnology.edu.iq.
Hani A Ba-AwadhDepartment of Animal Production, College of Food and Agriculture Sciences, King Saud University, Riyadh, 11451, Saudi Arabia.
Alaa B IsmaelDepartment of Clinical Laboratory Sciences, College of Applied Medical Sciences, Taif University, Taif, Saudi Arabia.
Ayman A SwelumDepartment of Animal Production, College of Food and Agriculture Sciences, King Saud University, Riyadh, 11451, Saudi Arabia. aswelum@ksu.edu.sa.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antibacterial activities of ZrO2, binary mixture (ZrO2+ Y2O3),and triple mixture (ZrO2 + Y2O3 + Al2O3) were studied against pathogenic bacterial strains, Escherichia coli and Staphylococcus aureus. The study also revealed the bacterial biofilm inhibition and biocompatibility of ZrO2 + Y2O3 + Al2O3. The triple mixture, composed of zirconium dioxide, yttrium trioxide, and aluminum trioxide (ZrO2 + Y2O3 + Al2O3), exhibited highest anti-bacterial effects against Staphylococcus aureus as compared with the Escherichia coli, with inhibition zone diameters of 27.33 mm and 22.66 mm, respectively. The binary mixture (ZrO2 + Y2O3) was comparable with the triple mixture in their antibacterial effects with the inhibition zone diameters of 24.66 mm and 21 mm as against Staphylococcus aureus, and Escherichia coli, respectively. Finally, the ZrO2 alone showed the lowest antibacterial effects. Furthermore, after 24 h of incubation at 37 °C, the three composites were also evaluated for the potential anti-adherence for the microbial biofilm in Streptococcus mutans. The results showed the adhesion process was decreased with increasing the concentrations of the triple mixture. Moreover, the in vitro biocompatibility evaluations in Rat Embryonic Fibroblast (REF) cells showed that the nanoparticles possessed low cytotoxicity, and indicated good biocompatibility. Hence, it was inferred that the synthesized Zirconia–Yttria triple mixture system can be useful for biomedical applications, especially in the field of dental implant techniques.

Indexed as

Aluminum OxideAnti-Bacterial AgentsMetal NanoparticlesNanoparticlesYttriumZirconiumAnimalsBacterial AdhesionBiofilmsEscherichia coliMicrobial Sensitivity TestsRatsStaphylococcus aureusStreptococcus mutansAluminum OxideAnti-Bacterial AgentsYttriumZirconiumzirconium oxideAnti-bacterialAnti-biofilm activityBiocompatibilityNano compositesTriple mixtureZirconia-yttria system

Identifiers

PMID42115210
PMCPMC13161406

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