Trial reportJournal of biophotonics2026
Antimicrobial Photodynamic Therapy in the Treatment of Diabetic Foot Ulcers: A Pilot Randomized Clinical Trial.
Trial report in Journal of biophotonics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This pilot randomized clinical trial evaluated photodynamic therapy (PDT) in diabetic foot ulcers (DFUs), comparing an intervention group (IG, n = 5) with a control group (CG, n = 4). Participants were followed for 7 weeks. The IG received PDT, while the CG underwent conventional care. The microbiological profile was assessed by biopsy before and after treatment, and wound progression was evaluated using the Bates-Jensen Wound Assessment Tool. In the IG, only one participant showed an increase in the number of bacterial species, while the others maintained the count with changes in species composition. In the CG, two participants presented an increase in bacterial species. All participants in the IG showed a reduction in ulcer size, with an average decrease of more than 63%, whereas two participants in the CG exhibited an increase in lesion area. These results suggest clinically relevant differences, supporting PDT as a promising adjuvant strategy for antimicrobial stewardship in DFUs.
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