Evidence map›Paper›PMID 42114115›Full record

SynthesisJournal of animal science2026

The impact of supplementing quebracho and chestnut tannin extracts on the growth performance in growing and finishing beef cattle: a meta-analytical assessment.

Mingyung Lee, Luis O Tedeschi

Abstract readMeta-Analysis
In one paragraph

Synthesis in Journal of animal science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

2 authors.

Mingyung LeeDepartment of Animal Science, Texas A&M University, College Station, TX 77843, USA.ORCID 0000-0001-8952-9725
Luis O TedeschiDepartment of Animal Science, Texas A&M University, College Station, TX 77843, USA.ORCID 0000-0003-1883-4911

Funding

USDA-NIFA #09123
6 · The paper itself

Abstract

Tannin extracts (TE), composed of condensed tannins from quebracho and hydrolyzable tannins from chestnut, have been studied as functional feed additives to improve growth performance in beef cattle, but reported effects vary with TE composition, dose, dietary protein, and co-additive. This meta-analysis evaluated TE supplementation effects on average daily gain (ADG), dry matter intake (DMI), and gain:feed (G:F) in growing and finishing beef cattle, using 162 treatment records from 43 published studies involving > 22,000 animals, mostly bulls and feedlot-based studies, including grazing and individually pen trials. Additional analyses included conditional independence tests for monensin use, forest and mosaic plots, and subset analyses for diets with or without monensin. Meta-regression indicated that TE supplementation was associated with increases in ADG (P < 0.001), DMI (P < 0.001), and G:F (P = 0.024). The ADG response was nonlinear; quadratic models indicated an optimal inclusion of ∼0.30% of dietary DM for maximizing weight gain. The disproportionate increase in ADG relative to DMI is consistent with improved nutrient utilization. The TE-ADG relationship was stronger at lower crude protein intake (P = 0.0525), however, because crude protein intake is not a direct proxy for rumen-degradable nitrogen supply and may co-vary with diet formulation and co-additives (e.g., ionophores and/or NPN sources), this pattern should be interpreted as context-dependent rather than as evidence of a universal mechanism. A conditional independence test also suggested that the TE-associated ADG responses were not independent of monensin use, suggesting a possible synergy effect, though additional studies are needed to confirm this pattern. Overall, TE appears to be a context-dependent additive rather than a universal growth promoter, and responses did not necessarily require doses near the model-derived optimum; benefits were also detectable at lower inclusions (e.g., ∼0.08% of dietary DM) in some contexts. Further research is needed to refine dosing strategies, better characterize TE chemistry, and evaluate environmental outcomes in dedicated studies.

Indexed as

FagaceaePlant ExtractsTanninsAnimal FeedAnimal Nutritional Physiological PhenomenaAnimalsCattleDietDietary SupplementsPlant ExtractsTanninsgrowing and finishing beef cattlegrowth performancemeta-analysismeta-regressiontannin extract

Identifiers

PMID42114115
PMCPMC13188999

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.