Evidence map›Paper›PMID 42113979›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2026

Sperm, egg, and embryo proteins critical for genetic adaptation of herring to low salinity in the Baltic Sea.

Cheng Ma, Fahime Mohamadnejad Sangdehi, Mari Kawaguchi, Kaori Sano, Svenja V Dannenberg, Mats E Pettersson, Andreas Wallberg, Joshua L Wort, Yumeng Yan, Sergei Moshkovskii and 7 more

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Sperm, egg, and embryo proteins critical for genetic adaptation of herring to low salinity in the Baltic Sea.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Cheng Ma *Department of Medical Biochemistry and Microbiology, Uppsala University, Uppsala 75123, Sweden.ORCID 0000-0002-9289-9791
Fahime Mohamadnejad Sangdehi *Department of Medical Biochemistry and Microbiology, Uppsala University, Uppsala 75123, Sweden.
Mari Kawaguchi *Department of Materials and Life Sciences, Faculty of Science and Technology, Sophia University, Tokyo 102-8554, Japan.
Kaori Sano *Department of Chemistry and Biological Science, Faculty of Science, Josai University, Saitama 350-0295, Japan.ORCID 0000-0002-0435-4143
Svenja V Dannenberg *Bioanalytical Mass Spectrometry Research Group, Max Planck Institute for Multidisciplinary Sciences, Göttingen 37077, Germany.
Mats E PetterssonDepartment of Medical Biochemistry and Microbiology, Uppsala University, Uppsala 75123, Sweden.ORCID 0000-0002-7372-9076
Andreas WallbergDepartment of Medical Biochemistry and Microbiology, Uppsala University, Uppsala 75123, Sweden.
Joshua L WortLife & Medical Sciences Institute, Unit 4: Chemical Biology and Medicinal Chemistry, University of Bonn, Bonn 53115, Germany.
Yumeng YanBioanalytical Mass Spectrometry Research Group, Max Planck Institute for Multidisciplinary Sciences, Göttingen 37077, Germany.
Sergei MoshkovskiiBioanalytical Mass Spectrometry Research Group, Max Planck Institute for Multidisciplinary Sciences, Göttingen 37077, Germany.
Florian BergInstitute of Marine Research, Bergen N-5817, Norway.ORCID 0000-0003-1543-8112
Arild FolkvordInstitute of Marine Research, Bergen N-5817, Norway.ORCID 0000-0002-4763-0590
Christof LenzBioanalytical Mass Spectrometry Research Group, Max Planck Institute for Multidisciplinary Sciences, Göttingen 37077, Germany.
Henning UrlaubBioanalytical Mass Spectrometry Research Group, Max Planck Institute for Multidisciplinary Sciences, Göttingen 37077, Germany.ORCID 0000-0003-1837-5233
U Benjamin KauppLife & Medical Sciences Institute, Unit 4: Chemical Biology and Medicinal Chemistry, University of Bonn, Bonn 53115, Germany.
Shigeki YasumasuDepartment of Materials and Life Sciences, Faculty of Science and Technology, Sophia University, Tokyo 102-8554, Japan.ORCID 0000-0003-4295-477X
Leif AnderssonDepartment of Medical Biochemistry and Microbiology, Uppsala University, Uppsala 75123, Sweden.ORCID 0000-0002-4085-6968

Funding

Deutsche Forschungsgemeinschaft (DFG) 469281184 P04Knut och Alice Wallenbergs Stiftelse (kawforskning) 2023.0160Knut och Alice Wallenbergs Stiftelse (kawforskning) 2024.0058MEXT | Japan Society for the Promotion of Science (JSPS) 22K06303MEXT | Japan Society for the Promotion of Science (JSPS) 22K06344MEXT | Japan Society for the Promotion of Science (JSPS) 23K05879Vetenskapsrådet (VR) 2017-02907
6 · The paper itself

Abstract

How species genetically adapt to new environments is a central question in evolutionary biology. Here whole-genome sequencing combined with functional analysis is used to dissect how Atlantic herring, a marine fish, has adapted to the brackish Baltic Sea. Genes involved in reproduction and early development emerge as primary targets of natural selection, with key changes in a sperm-specific anion channel (

Indexed as

Adaptation, PhysiologicalFishesFish ProteinsOvumSalinitySpermatozoaAnimalsSelection, GeneticTransglutaminasesFish ProteinsTransglutaminasesecological adaptationgenome biologymolecular evolutionnatural selectionreproduction

Identifiers

PMID42113979
PMCPMC13187792

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.