Evidence map›Paper›PMID 42113885›Full record

ArticlePloS one2026

Host plant nutrition drives fitness outcomes in the cactus specialist Drosophila mettleri.

Lidane Noronha, Brian P Lazzaro, Patrick M O'Grady

Abstract read
In one paragraph

Article in PloS one, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Lidane NoronhaDepartment of Entomology, Cornell University, Ithaca, New York, United States of America.ORCID https://orcid.org/0000-0001-6761-1648
Brian P LazzaroDepartment of Entomology, Cornell University, Ithaca, New York, United States of America.ORCID https://orcid.org/0000-0002-3881-0995
Patrick M O'GradyDepartment of Entomology, Cornell University, Ithaca, New York, United States of America.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Organisms must navigate complex interactions with host plants, microbial communities, and environmental cues to ensure their survival and reproductive success when adapting to novel environments. Due to their ecological constraints, host plant specialists can be used to study how these interactions affect fitness due to their ecological constraints. In specialist species, such as cactophilic Drosophila, it remains unclear how feeding behavior, substrate composition, and microbial interactions collectively shape fitness outcomes. We examined the effects of laboratory media (cornmeal vs. banana) differing in their base diet and cactus-derived additives (dried Saguaro powder, exudate from rotting Saguaro, soil soaked by rotting Saguaro) on fitness in Drosophila mettleri, a columnar cactus specialist that breeds in Saguaro cactus (Carnegiea gigantea) in the Sonoran Desert. Cactus supplements often reduced survival from egg to pupa, but increased survival from pupa to adult, resulting in stage specific tradeoffs shaping egg-to-adult fitness. Results show interactions between food substrate and cactus treatment: cactus supplementation reduced survival on banana media but increased survival on cornmeal-based diets. Feeding rate and overall amount of media consumed did not differ among treatments, indicating that differences in survival and fitness may depend on the broader nutritional environment and developmental stage. This suggests that studying host specialization should include multiple life stages.

Indexed as

CactaceaeDrosophilaGenetic FitnessAnimalsFeeding BehaviorFemale

Identifiers

PMID42113885
PMCPMC13160323

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.