Evidence map›Paper›PMID 42113853›Full record

ArticleGlobal spine journal2026

Nationwide Comparison of 2 year Revision Surgery Risk After Hybrid Cervical Surgery with 2-Level ACDF and 2-Level CDR Surgical Technique.

Ali Issani, Aidan Lindgren, Daniel Rusu, Raymond J Hah, Ram Kiran Alluri, Jeffrey Wang

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Article in Global spine journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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0 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Ali IssaniDepartment of Orthopaedic Surgery, Keck Medicine of USC, Los Angeles, CA, USA.ORCID 0000-0003-0674-2294
Aidan LindgrenDepartment of Orthopaedic Surgery, Keck Medicine of USC, Los Angeles, CA, USA.
Daniel RusuDepartment of Orthopaedic Surgery, Keck Medicine of USC, Los Angeles, CA, USA.ORCID 0009-0005-5916-0484
Raymond J HahDepartment of Orthopaedic Surgery, Keck Medicine of USC, Los Angeles, CA, USA.ORCID 0000-0001-7513-3519
Ram Kiran AlluriDepartment of Orthopaedic Surgery, Keck Medicine of USC, Los Angeles, CA, USA.ORCID 0000-0001-5919-707X
Jeffrey WangDepartment of Orthopaedic Surgery, Keck Medicine of USC, Los Angeles, CA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Study designRetrospective cohort study.ObjectiveTo perform a retrospective study comparing 2 level hybrid surgery (1 level ACDF and 1 level CDR) with 2 level ACDF and 2 level CDR.MethodsPatients undergoing first-instance two-level cervical spine surgery were identified using CPT codes and grouped into ACDF, CDR, or hybrid (single-level ACDF + single-level CDR) cohorts, with exclusions for posterior fusion, trauma, infection, malignancy, prior revision, and overlapping procedures. Revision surgery was defined as any cervical operation within two years of the index procedure, and baseline variables included demographics, comorbidities (Elixhauser Comorbidity Index), cervical pathology, insurance type, tobacco history and osteoporosis. Comparisons were performed using t-tests and chi-square tests, and adjusted Cox proportional hazards models and Kaplan-Meier analysis were used to evaluate two-year revision risk and revision-free survival among cohorts.ResultAmong 122,164 patients, ACDF patients were older and had greater comorbidity burden and higher rates of myelopathy and osteoporosis, with overall secondary cervical procedures most frequent after two-level ACDF. On multivariable analysis, myelopathy, tobacco history and osteoporosis were independently associated with increased revision risk, while insurance status was not. Surgical approach (ACDF, CDR, or hybrid) was not independently associated with two-year revision risk, and Kaplan-Meier analysis showed no significant differences in revision-free survival among cohorts.ConclusionSurgical approach (ACDF, CDR, or hybrid) was not independently associated with differences in two-year revision risk.

Indexed as

ACDF, cervical disc replacementhybrid cervical surgeryrevision surgery

Identifiers

PMID42113853
PMCPMC13161038

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.