Evidence map›Paper›PMID 42113841›Full record

ArticlePloS one2026

Toward Industry 5.0: A WebSocket-S7 Bridge for Low-Latency, IEC 61588-Compliant Digital Twins in Remote Industrial Automation.

Mohammed Hlayel, Hairulnizam Mahdin, Mohammad Hayajneh, Heru Nurwarsito

Abstract read
In one paragraph

Article in PloS one, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Mohammed HlayelFatima College of Health Sciences, Institute of Applied Technology, Abu Dhabi, UAE.ORCID https://orcid.org/0000-0002-3410-3679
Hairulnizam MahdinFaculty of Computer Science and Information Technology, Universiti Tun Hussein Onn Malaysia, Parit Raja, Johor, Malaysia.
Mohammad HayajnehCollege of Information Technology, United Arab Emirates University, Al-Ain, Abu Dhabi, UAE.
Heru NurwarsitoFaculty of Computer Science, University of Brawijaya, Malang, Indonesia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

While Industry 4.0 established connectivity and automation as foundations of smart factories, the emerging vision of Industry 5.0 emphasizes human-centric, resilient, and sustainable systems. Within this evolution, integrating Digital Twins (DTs) with Programmable Logic Controllers (PLCs) in cloud environments remains constrained by the lack of communication protocols that satisfy strict real-time requirements. To address this gap, this paper introduces and validates a WebSocket-S7 protocol bridge for low-latency, full-duplex communication between Siemens S7 PLCs and cloud-hosted DT models. The main contribution of this work is the design and experimental validation of a lightweight, event-driven WebSocket-S7 architecture. This architecture decouples real-time PLC execution from cloud-based digital twin interaction, enabling deterministic performance over wide-area networks without relying on brokers or polling mechanisms. A comprehensive evaluation compares the proposed bridge with MQTT, OPC UA, and Modbus for real-time PLC-DT interactions managed through Node-RED. Using AWS as the cloud backend, the study assesses performance, scalability, and stability under single-user and multi-user emulated loads. Protocols were profiled using JMeter (load and latency), Wireshark (packet traces), and the Unity Profiler (CPU/memory on Android), with timing judged against IEC 61588 ([Formula: see text]). In remote cloud deployment, WebSocket-S7 achieved an average round-trip time (RTT) of 87 ms, remaining within the IEC 61588 threshold. It outperformed alternative protocols by clear margins-34.6% lower RTT than MQTT (133 ms), 46.3% lower than OPC UA (162 ms), and 55.2% lower than Modbus (194 ms), yielding absolute gains of 46, 75, and 107 ms, respectively. Under multi-user emulation, WebSocket-S7 maintained sub-100 ms average response times for up to 40 concurrent users with near-zero error rates, while MQTT offered a balanced option for moderate-throughput scenarios. These trends reflect WebSocket's lightweight framing and persistent, broker-less transport. Together, these characteristics minimize connection overhead and jitter in WAN conditions. The findings position WebSocket-S7 as a lightweight and scalable solution for remote DT-PLC integration, particularly when standardized protocols incur higher overhead. By consistently meeting IEC-compliant timing requirements, the proposed bridge provides a practical and robust foundation for deploying real-time digital twins in both educational and industrial automation settings.

Indexed as

AutomationIndustryCloud ComputingComputer Communication NetworksInformation Technology

Identifiers

PMID42113841
PMCPMC13160324

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.