Evidence map›Paper›PMID 42113786›Full record

ArticlePLOS digital health2026

The emerging role of digital dentistry in managing molar-incisor hypomineralization: A perspective.

Cinthya Jeanette Arias Guillén, Ulysses de Toledo Monteiro, Anna Laura Doalto, João Sarmento Pereira Neto, Regina Maria Puppin-Rontani, Aline Castilho

Abstract read
In one paragraph

Article in PLOS digital health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Cinthya Jeanette Arias GuillénDepartamento‌‌ de Saúde Coletiva, Odontopediatria e Ortodontia, Faculdade de Odontologia de Piracicaba, Universidade Estadual de Campinas, Piracicaba, São Paulo, Brasil.
Ulysses de Toledo MonteiroDepartamento‌‌ de Odontologia Restauradora, Faculdade de Odontologia de Piracicaba, Universidade Estadual de Campinas, Piracicaba, São Paulo, Brasil.
Anna Laura DoaltoFaculdade de Odontologia de Piracicaba, Universidade Estadual de Campinas, Piracicaba, São Paulo, Brasil.
João Sarmento Pereira NetoDepartamento de Saúde Coletiva, Odontopediatria e Ortodontia, Faculdade de Odontologia de Piracicaba, Universidade Estadual de Campinas, Piracicaba, São Paulo, Brasil.ORCID https://orcid.org/0000-0002-5843-9302
Regina Maria Puppin-RontaniDepartamento de Saúde Coletiva, Odontopediatria e Ortodontia, Faculdade de Odontologia de Piracicaba, Universidade Estadual de Campinas, Piracicaba, São Paulo, Brasil.
Aline CastilhoDepartment of Pediatric Dentistry, Indiana University School of Dentistry, Indianapolis, Indiana, United States of America.ORCID https://orcid.org/0000-0003-4704-6973

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Molar-incisor hypomineralization (MIH) remains one of the most challenging conditions in pediatric dentistry, with fragile enamel that compromises structural integrity, patient comfort, and the longevity of traditional restorative treatments. The unpredictable bonding to hypomineralized substrates results in frequent restoration failures, reinforcing the need for new approaches. In this opinion piece, we argue that digital dentistry offers promising strategies to improve precision, durability, and patient-centered care in MIH management. Drawing on a clinical case used as a proof of concept to illustrate feasibility, we describe a fully digital workflow including intraoral scanning, CAD/CAM design, and 3D-printed indirect restoration. Digital workflows may also enrich dental education by familiarizing students with emerging technologies. At the same time, we acknowledge key barriers such as cost, accessibility, and the clinician learning associated with digital adoption. Digital solutions hold promise as part of a broader strategy to improve care for patients with MIH.

Identifiers

PMID42113786
PMCPMC13160353

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.