In one paragraphArticle in Epilepsia, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
17 authors.
Wei DuanDepartment of Neurology, Huashan Hospital, Institute for Translational Brain Research, Center for Clinical Neuro-AI, State Key Laboratory of Brain Function and Disorders, Ministry of Education Frontiers Center for Brain Science, Fudan University, Shanghai, China.ORCID https://orcid.org/0009-0006-7045-9935 Zongyi XuDepartment of Neurology, Huashan Hospital, Institute for Translational Brain Research, Center for Clinical Neuro-AI, State Key Laboratory of Brain Function and Disorders, Ministry of Education Frontiers Center for Brain Science, Fudan University, Shanghai, China.ORCID https://orcid.org/0009-0009-4938-0079 Suixin DengSchool of Life Sciences, Ministry of Education Key Laboratory of Rare Pediatric Diseases, Hunan Key Laboratory of Animal Models for Human Diseases, Central South University, Changsha, China.ORCID https://orcid.org/0000-0003-4795-2570 Wei KeDepartment of Neurology, Huashan Hospital, Institute for Translational Brain Research, Center for Clinical Neuro-AI, State Key Laboratory of Brain Function and Disorders, Ministry of Education Frontiers Center for Brain Science, Fudan University, Shanghai, China.ORCID https://orcid.org/0009-0002-8248-4338 Xiaoxue ZhangDepartment of Neurology, Huashan Hospital, Institute for Translational Brain Research, Center for Clinical Neuro-AI, State Key Laboratory of Brain Function and Disorders, Ministry of Education Frontiers Center for Brain Science, Fudan University, Shanghai, China.ORCID https://orcid.org/0009-0003-9260-0125 Shuyu YuanDepartment of Neurology, Huashan Hospital, Institute for Translational Brain Research, Center for Clinical Neuro-AI, State Key Laboratory of Brain Function and Disorders, Ministry of Education Frontiers Center for Brain Science, Fudan University, Shanghai, China.ORCID https://orcid.org/0009-0003-9701-482X Kexin WangDepartment of Neurology, Huashan Hospital, Institute for Translational Brain Research, Center for Clinical Neuro-AI, State Key Laboratory of Brain Function and Disorders, Ministry of Education Frontiers Center for Brain Science, Fudan University, Shanghai, China.ORCID https://orcid.org/0009-0001-1654-2926 Liang LiDepartment of Neurology, Huashan Hospital, Institute for Translational Brain Research, Center for Clinical Neuro-AI, State Key Laboratory of Brain Function and Disorders, Ministry of Education Frontiers Center for Brain Science, Fudan University, Shanghai, China.ORCID https://orcid.org/0009-0006-2321-7853 Haidong D LuDepartment of Neurology, Huashan Hospital, Institute for Translational Brain Research, Center for Clinical Neuro-AI, State Key Laboratory of Brain Function and Disorders, Ministry of Education Frontiers Center for Brain Science, Fudan University, Shanghai, China.ORCID https://orcid.org/0000-0003-1739-9508 Quansheng HeDepartment of Neurology, Huashan Hospital, Institute for Translational Brain Research, Center for Clinical Neuro-AI, State Key Laboratory of Brain Function and Disorders, Ministry of Education Frontiers Center for Brain Science, Fudan University, Shanghai, China.ORCID https://orcid.org/0000-0002-0235-0843 Yousheng ShuDepartment of Neurology, Huashan Hospital, Institute for Translational Brain Research, Center for Clinical Neuro-AI, State Key Laboratory of Brain Function and Disorders, Ministry of Education Frontiers Center for Brain Science, Fudan University, Shanghai, China.ORCID https://orcid.org/0000-0002-2834-2876 Funding
Brain Science and Brain-like Intelligence Technology-National Science and Technology Major Project 2021ZD0202500National Natural Science Foundation of China 32100930National Natural Science Foundation of China 32130044National Natural Science Foundation of China T2241002Program of Shanghai Academic/Technology Research Leader 21XD1400100
6 · The paper itselfAbstract
objectiveThis study was undertaken to investigate the mechanisms underlying the paradoxical phenomena of excessive neurotransmitter release and suppressed sodium-spike generation due to depolarization block (DB) during seizure activity.
methodsWe employed acute neocortical slices from mice to investigate DB in pyramidal cells (PCs) during epileptiform activity (EA). Local high-K
resultsMembrane potential levels of DB in PCs during EA remained constant even with strong hyperpolarization, suggesting dependence on an ionic reversal potential. Local high-K SIGNIFICANCE: Our findings demonstrate that, during epileptiform activity, DB is predominantly determined by excessive accumulation of extracellular K
Indexed as
DopamineGlutamic AcidNeocortexNeurotransmitter AgentsPyramidal CellsSeizuresAnimalsAxonsKindling, NeurologicMaleMembrane PotentialsMiceMice, Inbred C57BLPotassiumSynaptic TransmissionDopamineGlutamic AcidNeurotransmitter AgentsPotassiumaxon terminalsdepolarization blockepilepsyextracellular potassiumsynaptic transmission
Identifiers
PMID42113533
PMCPMC13525585
What OpenQuestion holds
Textmetadata
Read underepoch 390