Evidence map›Paper›PMID 42113417›Full record

ArticleAnnals of nuclear medicine2026

Phantom-based optimization of [

Takuro Shiiba, Hiroyuki Azuma, Kento Maeda, Shingo Tanahashi, Masanori Watanabe, Kosuke Yamashita, Masakazu Tsujimoto, Shigeo Ohba, Yoshitaka Inui, Hiroshi Toyama

Abstract read
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In one paragraph

Article in Annals of nuclear medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Takuro ShiibaDepartment of Medical Image Analysis, Division of Advanced Biomedical Sciences, Faculty of Life Sciences, Kumamoto University, 4-24-1, Kuhonji, Chuo-Ku, Kumamoto, 862- 0976, Japan. shiiba@kumamoto-u.ac.jp.ORCID http://orcid.org/0000-0001-5515-091X
Hiroyuki AzumaDepartment of Radiology, Fujita Health University Hospital, 1-98, Dengakubo, Kutsukake-Cho, Toyoake, 470-1192, Aichi, Japan.
Kento MaedaDepartment of Radiology, Fujita Health University Hospital, 1-98, Dengakubo, Kutsukake-Cho, Toyoake, 470-1192, Aichi, Japan.
Shingo TanahashiDepartment of Radiology, Fujita Health University Hospital, 1-98, Dengakubo, Kutsukake-Cho, Toyoake, 470-1192, Aichi, Japan.
Masanori WatanabeDepartment of Radiology, Fujita Health University Hospital, 1-98, Dengakubo, Kutsukake-Cho, Toyoake, 470-1192, Aichi, Japan.
Kosuke YamashitaDepartment of Medical Imaging Technology, Division of Advanced Biomedical Sciences, Faculty of Life Sciences, Kumamoto University, 4-24-1, Kuhonji, Chuo-Ku, Kumamoto, 862- 0976, Japan.
Masakazu TsujimotoDepartment of Medical Equipment Engineering, School of Medical Sciences, Fujita Health University, 1-98, Dengakubo, Kutsukake-Cho, Toyoake, 470-1192, Aichi, Japan.
Shigeo OhbaDepartment of Neurosurgery, Fujita Health University, 1‑98 Dengakugakubo, Kutsukake‑Cho, Toyoake, 470‑1192, Aichi, Japan.
Yoshitaka InuiDepartment of Radiology, Fujita Health University, 1‑98 Dengakugakubo, Kutsukake‑Cho, Toyoake, 470‑1192, Aichi, Japan.
Hiroshi ToyamaDepartment of Radiology, Fujita Health University, 1‑98 Dengakugakubo, Kutsukake‑Cho, Toyoake, 470‑1192, Aichi, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis study aimed to establish and evaluate two evidence-based reconstruction protocols for [

methodsA brain-tumor phantom (target-to-background ratio, 5:1) was scanned on a dedicated head PET scanner (BresTome, Shimadzu). Using a 60-min list-mode acquisition, parameters were optimized for two visually defined pathways (10-min clinical-efficiency; 30-min high-quality). The optimization sequence involved optimizing the relaxation factor (β) using mean percent contrast (%contrast

resultsTwo distinct protocols were established. The 10-min clinical-efficiency protocol was optimized with β = 60 and an NLM filter (intensity 1.5), which provided the best CNR for the 7.5-mm sphere. The 30-min high-quality protocol was optimized with β = 70 and an NLM filter (intensity 1.0), which yielded the highest CNR for the 5-mm sphere. The 30-min protocol was required for enhanced visibility of the 5-mm sphere. Both protocols met the Japanese criteria for %contrast

conclusionThis study establishes a dual-pathway framework for [

Indexed as

Brain NeoplasmsCarboxylic AcidsCyclobutanesHeadImage Processing, Computer-AssistedPhantoms, ImagingPositron-Emission TomographyHumansSignal-To-Noise RatioCarboxylic AcidsCyclobutanesfluciclovine F-18[18F]fluciclovineAmino acidDedicated head PETLM-DRAMANeuro-oncologyNon-local means

Identifiers

PMID42113417

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.