Evidence map›Paper›PMID 42113241›Full record

ArticleEuropean radiology2026

Percutaneous image-guided cryoablation of umbilical endometriosis: safety, feasibility, clinical, and imaging outcomes.

Anne-Charlotte de Rycke, Alexandre Faure, Milan Najdawi, Raphael Lehrer, Raphael Di Giuseppe, Alexis Nobileau, Cyril Touboul, Yohann Dabi, François H Cornelis, Isabelle Thomassin-Naggara and 1 more

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Article in European radiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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4 · The record

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5 · Who and what money

Authors and funding

11 authors.

Anne-Charlotte de RyckePublic Hospital of Paris (AP-HP), Radiology Imaging and Interventional Radiology Specialized Department, Tenon Hospital, Sorbonne University, Paris, France.
Alexandre FaurePublic Hospital of Paris (AP-HP), Radiology Imaging and Interventional Radiology Specialized Department, Tenon Hospital, Sorbonne University, Paris, France.
Milan NajdawiPublic Hospital of Paris (AP-HP), Radiology Imaging and Interventional Radiology Specialized Department, Tenon Hospital, Sorbonne University, Paris, France.
Raphael LehrerPublic Hospital of Paris (AP-HP), Radiology Imaging and Interventional Radiology Specialized Department, Tenon Hospital, Sorbonne University, Paris, France.
Raphael Di GiuseppePublic Hospital of Paris (AP-HP), Radiology Imaging and Interventional Radiology Specialized Department, Tenon Hospital, Sorbonne University, Paris, France.
Alexis NobileauPublic Hospital of Paris (AP-HP), Radiology Imaging and Interventional Radiology Specialized Department, Tenon Hospital, Sorbonne University, Paris, France.
Cyril TouboulSaint-Antoine Research Center (CRSA), INSERM UMR-S 938, CNRS, Sorbonne University, Paris, France.
Yohann DabiSaint-Antoine Research Center (CRSA), INSERM UMR-S 938, CNRS, Sorbonne University, Paris, France.
François H CornelisDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Isabelle Thomassin-NaggaraPublic Hospital of Paris (AP-HP), Radiology Imaging and Interventional Radiology Specialized Department, Tenon Hospital, Sorbonne University, Paris, France.
Léo RazakamanantsoaPublic Hospital of Paris (AP-HP), Radiology Imaging and Interventional Radiology Specialized Department, Tenon Hospital, Sorbonne University, Paris, France. leo.razakamanantsoa@aphp.fr.ORCID http://orcid.org/0000-0002-4524-4901

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo evaluate the safety, feasibility and imaging outcomes of percutaneous image-guided cryoablation as a minimally invasive treatment for umbilical endometriosis (UE). MATERIALS AND

methodsBetween March 2017 and December 2024, 17 women (median age: 38 years; [IQR, 32-38]) underwent percutaneous cryoablation of UE at a single institution. Procedures were performed under ultrasound (US) alone or combined US/CT-scan guidance. Pain severity was assessed using the visual analog scale (VAS), imaging (US and MRI) and cosmetic outcomes were compared before and after treatment. Adverse events were reported according to the Society of Interventional Radiology classification (SIR).

resultsMedian lesion volume was 2.42 cm

conclusionPercutaneous image-guided cryoablation appears to be safe and feasible for umbilical endometriosis, offering significant pain relief, substantial nodule volume reduction and satisfactory cosmetic outcomes with predominantly minor adverse events. KEY POINTS: Question Umbilical endometriosis causes disabling pain and cosmetic concerns. Surgical excision is invasive and minimally invasive image-guided alternatives with proven efficacy and safety remain lacking. Findings Percutaneous cryoablation of umbilical endometriosis achieved durable pain relief (82%), significant nodule reduction (73%), and high cosmetic satisfaction in 82% of patients, with few adverse events, confirming its feasibility and safety. Clinical relevance Percutaneous cryoablation represents a minimally invasive, outpatient alternative to surgery for umbilical endometriosis, offering durable symptom relief and improved cosmetic outcomes, with low morbidity, potentially improving patients' quality of life and broadening therapeutic options for this rare entity.

Indexed as

CryosurgeryEndometriosisSurgery, Computer-AssistedUmbilicusAdultFeasibility StudiesFemaleHumansMagnetic Resonance ImagingTomography, X-Ray ComputedTreatment OutcomeUltrasonography, InterventionalCryoablationInterventional radiologyMagnetic resonance imagingPain managementUmbilical endometriosis

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.