Evidence map›Paper›PMID 42113229›Full record

ArticlePediatric surgery international2026

Efficacy of modified tubularized incised plate urethroplasty for hypospadias.

Nuoxian Li, Shengli Zhang, Luping Li, Pengpeng Liu, Yuchen Liu, Chunyu Chen, Junxiang Li, Boyuan Wang, Liang Hao, Yasen Wei and 1 more

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Article in Pediatric surgery international, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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4 · The record

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5 · Who and what money

Authors and funding

11 authors.

Nuoxian LiDepartment of Pediatric Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, China.
Shengli ZhangDepartment of Pediatric Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, China. unfail007@163.com.
Luping LiDepartment of Pediatric Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, China.
Pengpeng LiuDepartment of Pediatric Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, China.
Yuchen LiuDepartment of Pediatric Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, China.
Chunyu ChenDepartment of Pediatric Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, China.
Junxiang LiDepartment of Pediatric Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, China.
Boyuan WangDepartment of Pediatric Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, China.
Liang HaoDepartment of Pediatric Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, China.
Yasen WeiDepartment of Pediatric Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, China.
Yingzhong FanDepartment of Pediatric Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, China.

Funding

Key Scientific Research Project of Higher Education Institutions of Henan Province 24A320020
6 · The paper itself

Abstract

purposeTo evaluate the clinical outcomes of tubularized incised plate urethroplasty (TIPU) combined with dissection of the urethral plate and distal urethral mobilization in children with mid-to-distal hypospadias.

methodsThis retrospective study included 183 pediatric patients with hypospadias who underwent primary repair between March 2021 and March 2023. Patients were divided into two groups according to the surgical technique: the modified TIPU group (mTIPU, n = 86) and the conventional TIPU group (cTIPU, n = 97). Baseline characteristics, perioperative parameters, postoperative complications, penile appearance scores, and uroflowmetry parameters were compared between the two groups.

resultsBaseline characteristics were comparable between the two groups (all P > 0.05). The mTIPU group had a longer operative time and a greater estimated blood loss (EBL) than the cTIPU group (both P < 0.05). However, no statistical difference was observed in the overall incidence of postoperative complications between the groups (P > 0.05). At the 2-year follow-up, patients in the mTIPU group demonstrated higher penile appearance scores for perceived penile straightness and overall appearance (both P < 0.05). In addition, the maximum urinary flow rate (Qmax) and the average urinary flow rate (Qave) were higher, and the duration of micturition was shorter in the mTIPU group compared to the cTIPU group (all P < 0.001), while voided volume did not differ significantly between the two groups (P > 0.05).

conclusionIn children with mid-to-distal hypospadias, TIPU combined with urethral plate dissection and distal urethral mobilization may improve postoperative penile appearance and urinary flow parameters. No statistical difference in postoperative complication rates was observed between the two techniques.

Indexed as

HypospadiasPlastic Surgery ProceduresUrethraUrologic Surgical Procedures, MaleChildChild, PreschoolFollow-Up StudiesHumansInfantMalePostoperative ComplicationsRetrospective StudiesTreatment OutcomeDistal urethral mobilizationHypospadiasPenile appearanceTubularized incised plate urethroplastyUrethral plate dissectionUroflowmetry

Identifiers

PMID42113229

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.