Evidence map›Paper›PMID 42113209›Full record

ArticleIntensive care medicine2026

Extracorporeal membrane oxygenation, acute kidney injury, fluid balance, and continuous renal replacement therapy: Acute Disease Quality Initiative (ADQI) and Extracorporeal Life Support Organization (ELSO) joint consensus conference.

Katja M Gist, David T Selewski, Kianoush B Kashani, Ayse Akcan-Arikan, Gail Annich, Marta V Antonini, David Askenazi, Linda Awdishu, Brian C Bridges, Michael J Connor and 21 more

Abstract readConsensus Statement
PubMed Full text at PMC Publisher
In one paragraph

Article in Intensive care medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

31 authors.

Katja M Gist *Department of Pediatrics, University of Colorado Denver, Children's Hospital Colorado, Aurora, USA. Katja.gist@cuanschutz.edu.ORCID http://orcid.org/0000-0002-7427-670X
David T Selewski *Department of Pediatrics, University of Arkansas for Medical Sciences, Little Rock, USA.
Kianoush B KashaniDivision of Nephrology and Hypertension, Division of Pulmonary, Critical Care, Allergy & Sleep Medicine, Department of Medicine, Mayo Clinic, Rochester, USA.
Ayse Akcan-ArikanDepartment of Pediatrics, Baylor College of Medicine, Texas Children's Hospital, Houston, USA.
Gail AnnichDepartment of Pediatrics, University of Toronto, Sick Kids, Toronto, Canada.
Marta V AntoniniDepartment of Medical and Surgical Sciences (DIMEC), University of Bologna, Bologna, Italy.
David AskenaziDepartment of Pediatrics, University of Alabama at Birmingham, Birmingham, USA.
Linda AwdishuDepartment of Pharmacy Practice and Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, La Jolla, USA.
Brian C BridgesDepartment of Pediatrics, Medical University of South Carolina, Charleston, USA.
Michael J ConnorDepartment of Medicine, Emory University School of Medicine, Atlanta, USA.
Lui G ForniIntensive Care Unit, Royal Surrey NHS Foundation Trust, University of Surrey SChool of Medicine, Guildford, UK.
Dana Y FuhrmanDepartment of Critical Care and Pediatrics, University of Pittsburgh Medical Center, Children's Hospital of Pittsburgh, Pittsburgh, USA.
Stuart L GoldsteinDepartment of Pediatrics, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, USA.
Stephen M GorgaDepartment of Pediatrics, C.S. Mott Children's Hospital, University of Michigan, Ann Arbor, USA.
Pramod K GuruDepartment of Critical Care Medicine, Mayo Clinic, Jacksonville, USA.
Ahmad KaddourahDepartment of Pediatrics, Sidra Medicine, Weill Cornell Medicine, Qatar College of Medicine, Qatar University, Doha, Qatar.
Alex Lepage-FarrellDepartment of Pediatrics, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, USA.
D Michael McMullanDivision of Pediatric Cardiothoracic Surgery, University of Washington, Seattle, USA.
Ravindra L MehtaDepartment of Medicine, University of California San Diego, San Diego, USA.
Shina MenonDepartment of Pediatrics, School of Medicine, Stanford University, Palo Alto, USA.
Theresa MottesDepartment of Pediatrics, Anna and Robert Lurie Children's Hospital, Chicago, USA.
Thomas MüellerDepartment of Internal Medicine II, University Hospital Regensburg, Bavaria, Germany.
Marlies OstermannDepartment of Critical Care, King's College London, Guy's & St Thomas' Hospital, London, UK.
Matthew L PadenDepartment of Pediatrics, Emory University School of Medicine, Atlanta, USA.
Natalie E RintoulDivision of Neonatology, Department of Pediatrics, The Children's Hospital of Philadelphia, The University of Pennsylvania Perelman School of Medicine, Philadelphia, USA.
Thiago ReisDivision of Nephrology, Clinical Research Center, University of São Paulo School of Medicine, São Paulo Brasil and CPQuali Pesquisa Clínica, São Paulo, Brazil.
Claudio RoncoDepartment of Nephrology, Dialysis and Transplantation, San Bortolo Hospital, International Renal Research Institute of Vicenza, Vicenza, Italy.
Emily SeeDepartment of Nephrology, University of Melbourne, Melbourne, Australia.
Gurmeet SinghDepartment of Critical Care Medicine and Division of Cardiac Surgery, Department of Surgery, Faculty of Medicine and Dentistry, University of Alberta, and Mazankowski Alberta Heart Institute, Alberta Health Services, Edmonton, Canada.
Sean M BagshawDepartment of Critical Care Medicine and Division of Cardiac Surgery, Department of Surgery, Faculty of Medicine and Dentistry, University of Alberta, and Mazankowski Alberta Heart Institute, Alberta Health Services, Edmonton, Canada.
Graeme MacLarenCardiothoracic Intensive Care Unit, National University Hospital, Singapore, Singapore.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Extracorporeal membrane oxygenation (ECMO) is increasingly being utilized for life-threatening cardiac and/or respiratory failure refractory to conventional treatment. Acute kidney injury (AKI) and fluid balance disorders commonly occur both before and during ECMO, with approximately half of cases receiving treatment with continuous renal replacement therapy (CRRT). Acute kidney injury, fluid balance disorders, and CRRT influence both short- and long-term outcomes in this population. The 36th Acute Disease Quality Initiative (ADQI) meeting was held in June 2025 to develop multidisciplinary international expert recommendations for AKI, fluid balance, and CRRT during ECMO across the age spectrum. This work encompassed five working groups: 1) epidemiology, risk factors, and outcomes of AKI and CRRT, 2) fluid management and outcomes, 3) indications for CRRT and fluid removal during ECMO, 4) best practices for performing CRRT during ECMO, and 5) biomarkers, extracorporeal blood purification, and drug pharmacokinetics and pharmacodynamics. As part of this work, knowledge gaps and research priorities were identified.

Indexed as

Acute Kidney InjuryContinuous Renal Replacement TherapyExtracorporeal Membrane OxygenationWater-Electrolyte BalanceHumansRenal Replacement TherapyRisk FactorsDialysisFluidKidneyOrgan failureRenalRenal support

Identifiers

PMID42113209
PMCPMC13269464

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.