Evidence map›Paper›PMID 42113121›Full record

ArticleJournal of enzyme inhibition and medicinal chemistry2026

Flavonoids from

Sang Seop Lee, Jang Hoon Kim, Kyonghwan Bang, Jin Yu, Yong Goo Kim, Sung Yeon Kim, Ik Soo Lee, Yung Choon Yoo

Abstract read
In one paragraph

Article in Journal of enzyme inhibition and medicinal chemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Sang Seop LeeDepartment of Microbiology, College of Medicine, Konyang University, Daejeon, Republic of Korea.
Jang Hoon KimDepartment of Herbal Crop Research, National Institute of Horticultural & Herbal Science, RDA, Eumseong, Republic of Korea.
Kyonghwan BangDepartment of Herbal Crop Research, National Institute of Horticultural & Herbal Science, RDA, Eumseong, Republic of Korea.
Jin YuDepartment of Herbal Crop Research, National Institute of Horticultural & Herbal Science, RDA, Eumseong, Republic of Korea.
Yong Goo KimDepartment of Herbal Crop Research, National Institute of Horticultural & Herbal Science, RDA, Eumseong, Republic of Korea.
Sung Yeon KimDepartment of Herbal Crop Research, National Institute of Horticultural & Herbal Science, RDA, Eumseong, Republic of Korea.
Ik Soo LeeKorea Institute of Oriental Medicine, Daejeon, Republic of Korea.
Yung Choon YooDepartment of Microbiology, College of Medicine, Konyang University, Daejeon, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PTP1B is a key negative regulator of insulin and leptin signalling and a promising therapeutic target for metabolic dysfunction, yet no clinically approved inhibitor exists due to selectivity and bioavailability challenges. To identify novel natural PTP1B inhibitors from

Indexed as

Enzyme InhibitorsFlavonoidsLamiaceaeProtein Tyrosine Phosphatase, Non-Receptor Type 1AnimalsDose-Response Relationship, DrugHepatocytesMiceMolecular Docking SimulationMolecular StructureOxidation-ReductionSignal TransductionStructure-Activity RelationshipEnzyme InhibitorsFlavonoidsProtein Tyrosine Phosphatase, Non-Receptor Type 1Elsholtzia ciliataflavonoidsmetabolic fluxPTP1B inhibitionredox homeostasis

Identifiers

PMID42113121
PMCPMC13162547

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.