Evidence map›Paper›PMID 42113109›Full record

ArticleJournal of psychopathology and clinical science2026

Test of the reward/circadian rhythm dysregulation model of risk for bipolar spectrum disorders at a micro time scale using multilevel moderated mediation.

Logan T Smith, Mackenzie A Maddox, Rachel F L Walsh, Joshua Klugman, Namni Goel, Lauren B Alloy

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of psychopathology and clinical science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Logan T SmithDepartment of Psychology and Neuroscience, Temple University.ORCID 0000-0002-2931-4236
Mackenzie A MaddoxDepartment of Psychology and Neuroscience, Temple University.
Rachel F L WalshDepartment of Psychology and Neuroscience, Temple University.
Joshua KlugmanDepartment of Sociology, Temple University.
Namni GoelDepartment of Psychiatry and Behavioral Sciences, Rush University Medical Center.
Lauren B AlloyDepartment of Psychology and Neuroscience, Temple University.ORCID 0000-0002-5196-2635

Funding

Risk for Bipolar Disorder: Reward-related Brain Function & Social RhythmsR01MH077908 · NIMH · TEMPLE UNIV OF THE COMMONWEALTH · PI ALLOY, LAUREN BERSH · 2007 to 2017
$5.7M
Integrated Reward-Circadian Rhythm Model of First Onset of Bipolar Spectrum Disorders in Adolescence SupplementR01MH126911 · NIMH · TEMPLE UNIV OF THE COMMONWEALTH · PI ALLOY, LAUREN BERSH, NUSSLOCK, ROBIN · 2021 to 2025
$3.8M
Impact of Daytime vs. Delayed Eating Schedule on Weight and Metabolic Markers Among Obese Persons: An Examination of Circadian MechanismsR01DK117488 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI ALLISON, KELLY C, GOEL, NAMNI · 2017 to 2021
$3.8M
Social and Circadian Rhythms, Reward Sensitivity, and Risk for Bipolar DisorderR01MH102310 · NIMH · TEMPLE UNIV OF THE COMMONWEALTH · PI ALLOY, LAUREN BERSH · 2014 to 2017
$1.6M
NIDDK NIH HHS R01 DK117488NIMH NIH HHS R01 MH077908NIMH NIH HHS R01 MH102310NIMH NIH HHS R01 MH126911
6 · The paper itself

Abstract

Two theories, the social zeitgeber theory and the reward theory, have been proposed to explain the onset of bipolar spectrum disorders (BSDs), highlighting the roles of disrupted sleep-wake rhythms and hypersensitivity to reward in BSDs. This study tested a component of the integrated reward/circadian rhythm dysregulation model of BSDs by examining how reward-relevant life events predict affective symptoms via social rhythm disruption (SRD) in young adults (

Indexed as

Bipolar DisorderChronobiology DisordersCircadian RhythmDepressionRewardAdolescentAdultEcological Momentary AssessmentFemaleHumansLife Change EventsMaleMediation AnalysisModels, PsychologicalYoung Adult

Identifiers

PMID42113109
PMCPMC13166091

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.