Evidence map›Paper›PMID 42112891›Full record

ArticleApplied and environmental microbiology2026

A novel cross-species vaccine design and nasal immunization strategy based on recombinant

Jiayi Hao, Xieshen Zhou, Guoqing Zhang, Lingcong Deng, Letian Li, Maopeng Wang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Applied and environmental microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jiayi Hao *College of Veterinary Medicine, Northwest A&F University, Yangling, China.
Xieshen Zhou *Wenzhou Key Laboratory for Virology and Immunology, Institute of Virology, Wenzhou University, Wenzhou, China.ORCID 0000-0002-0198-2224
Guoqing ZhangCollege of Animal Sciences, Key Laboratory for Zoonoses Research, Ministry of Education, Jilin University, Changchun, China.
Lingcong DengWenzhou Key Laboratory for Virology and Immunology, Institute of Virology, Wenzhou University, Wenzhou, China.
Letian LiState Key Laboratory of Pathogen and Biosecurity, Key Laboratory of Jilin Province for Zoonosis Prevention and Control, Changchun Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Changchun, China.ORCID 0000-0002-8743-0382
Maopeng WangWenzhou Key Laboratory for Virology and Immunology, Institute of Virology, Wenzhou University, Wenzhou, China.ORCID 0000-0001-8203-6645

Funding

CAMS Innovation Fund for Medical Sciences 2020-I2M-5-001Jilin Province Science and Technology Development Plan Project 20240602007RCNational Key Research and Development Program of China 2022YFC2604200National Natural Science Foundation of China 31802224
6 · The paper itself

Abstract

Porcine epidemic diarrhea (PED) is a highly lethal and airborne disease in neonatal piglets that has caused significant economic losses in the pig industry over the last three decades. Despite the widespread implementation of commercial vaccines, the disease continues to exhibit recurrent outbreaks, primarily owing to suboptimal immunization efficacy. In this study, we engineered recombinant

Indexed as

Coronavirus InfectionsLactiplantibacillus plantarumPorcine epidemic diarrhea virusSpike Glycoprotein, CoronavirusSwine DiseasesViral VaccinesAdministration, IntranasalAnimalsAntibodies, ViralFemaleImmunity, MucosalImmunizationMiceMice, Inbred BALB CSwineVaccines, SyntheticAntibodies, ViralSpike Glycoprotein, CoronavirusVaccines, SyntheticViral Vaccinescross-species vaccinationintranasal immunizationLactiplantibacillus plantarummucosal vaccinesPEDV

Identifiers

PMID42112891
PMCPMC13274380

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.