ArticleCardiovascular therapeutics2026
Association Between HALP Score and Atrial Fibrillation Recurrence After Radiofrequency Catheter Ablation.
Article in Cardiovascular therapeutics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Association Between HALP Score and Atrial Fibrillation Recurrence After Radiofrequency Catheter Ablation.Cardiovascular therapeutics · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
backgroundRadiofrequency catheter ablation (RFCA) is the primary treatment for atrial fibrillation (AF), but recurrence rates remain high. The hemoglobin, albumin, lymphocyte, and platelet (HALP) score reflects inflammation and nutrition, yet its prognostic value for AF recurrence remains unclear.
methodsWe retrospectively reviewed 877 patients with AF undergoing first RFCA. Patients were divided into four quartiles (Q1-Q4) based on preoperative HALP scores. Recurrence-free survival was estimated by Kaplan-Meier curves. Multivariate Cox models assessed the independent link between HALP scores and AF recurrence. Restricted cubic spline (RCS) analysis was conducted to explore the dose-response relationship. Model discrimination and reclassification were assessed using receiver operating characteristic (ROC) curve analysis, net reclassification improvement (NRI), and integrated discrimination improvement (IDI).
resultsA total of 686 patients with AF (mean age: 63.4 ± 10.7 years; 55.5% male) were included in the final analysis. The risk of AF recurrence demonstrated an inverse trend across HALP score quartiles (log-rank p < 0.001). After adjustment, patients in Q3 (HR = 0.45, 95% CI: 0.27-0.75) and Q4 (HR = 0.18, 95% CI: 0.08-0.38) had lower recurrence rates than those in Q1. RCS analysis revealed a linear inverse association between HALP score and the risk of AF recurrence. ROC analysis demonstrated that the HALP score alone exhibited significant discriminatory ability (AUC = 0.71, 95% CI: 0.66-0.75). Notably, incorporating the HALP score into a baseline model of 15 variables significantly improved model discrimination, increasing the AUC from 0.78 to 0.81 (p < 0.001). Furthermore, the addition of HALP score yielded significant improvements in reclassification (NRI = 0.19, IDI = 0.04; both p < 0.001).
conclusionsPreoperative HALP score is independently linked to AF recurrence after RFCA. Lower scores correspond to higher recurrence risk, suggesting its potential for enhanced risk stratification when combined with conventional clinical factors.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.