Evidence map›Paper›PMID 42112630›Full record

SynthesisJournal of the experimental analysis of behavior2026

Twenty-five years of simulated demand: A bibliometric and systematic review of hypothetical drug purchase tasks.

Derek D Reed, Justin C Strickland, Samuel F Acuff, Brett W Gelino, Madison E Graham, Brent A Kaplan, Alexandra Johansen, Zachary Pierce-Messick, Matthew L Banks, S Stevens Negus and 5 more

Abstract readSystematic Review
In one paragraph

Synthesis in Journal of the experimental analysis of behavior, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Derek D ReedInstitutes for Behavior Resources, Inc., Baltimore, MD, USA.ORCID https://orcid.org/0000-0002-5854-3425
Justin C StricklandDepartment of Psychiatry and Behavioral Science, The Johns Hopkins University School of Medicine, Baltimore, MD, USA.ORCID https://orcid.org/0000-0003-1077-0394
Samuel F AcuffDepartment of Psychiatry, Massachusetts General Hospital and Harvard Medical School, Recovery Research Institute, Boston, MA, USA.ORCID https://orcid.org/0000-0002-1934-2639
Brett W GelinoDepartment of Psychiatry, Robert Wood Johnson Medical School, Rutgers University, Piscataway, NJ, USA.ORCID https://orcid.org/0000-0001-8548-3627
Madison E GrahamDepartment of Applied Behavioral Science, Lawrence, KS, USA.ORCID https://orcid.org/0000-0002-2353-8415
Brent A KaplanCodedbx, Lexington, KY, USA.ORCID https://orcid.org/0000-0002-3758-6776
Alexandra JohansenDepartment of Psychology, University of Kentucky College of Arts and Sciences, Lexington, Kentucky, USA.ORCID https://orcid.org/0009-0003-2035-5642
Zachary Pierce-MessickDepartment of Psychiatry and Behavioral Science, The Johns Hopkins University School of Medicine, Baltimore, MD, USA.ORCID https://orcid.org/0000-0001-6765-0671
Matthew L BanksDepartment of Pharmacology and Toxicology, Virginia Commonwealth University, Richmond, VA, USA.ORCID https://orcid.org/0000-0003-4949-5246
S Stevens NegusDepartment of Pharmacology and Toxicology, Virginia Commonwealth University, Richmond, VA, USA.ORCID https://orcid.org/0000-0001-8471-645X
David N KearnsPsychology Department, American University, Washington, DC.
Dominic ChiapperinoCenter for Drug Evaluation and Research, Food and Drug Administration, United States Department of Health and Human Services, Silver Spring, MD, USA.
Chad J ReissigCenter for Drug Evaluation and Research, Food and Drug Administration, United States Department of Health and Human Services, Silver Spring, MD, USA.
Neil B VarshneyaCenter for Drug Evaluation and Research, Food and Drug Administration, United States Department of Health and Human Services, Silver Spring, MD, USA.ORCID https://orcid.org/0000-0003-3181-9580
Steven R HurshInstitutes for Behavior Resources, Inc., Baltimore, MD, USA.ORCID https://orcid.org/0000-0002-5391-2842

Funding

Intramural FDA HHS FD999999U.S. Food and Drug Administration PIID 75F40124P00127
6 · The paper itself

Abstract

Since its introduction by Jacobs and Bickel (1999), the hypothetical purchase task (HPT) has emerged as a frequently used methodology in behavioral economics research, particularly in studies of substance use and public health decision making. The HPT represents an approach that seeks to quantify the reinforcing value of drugs and other commodities through parametric, scalable methodology measured via self-reported consumption across escalating prices. Despite its increasing use in research settings, no comprehensive evaluation of its scientific influence has yet been undertaken. To address this gap, we conducted a two-part review of the HPT's empirical legacy. In Study 1, we conducted a bibliometric analysis of all peer-reviewed documents citing Jacobs and Bickel (1999) through mid-2025. In Study 2, we conducted a systematic review of empirical HPT studies employing operant demand analyses to assess drug consumption. We conclude with a discussion on the legacy of Jacobs and Bickel (1999), an evaluation of the present state of the field of operant behavioral economic science in addiction, and a call for critical areas of inquiry in the use of HPTs to measure drug abuse potential.

Indexed as

BibliometricsEconomics, BehavioralSubstance-Related DisordersCommerceHumansReinforcement, Psychologybehavioral economicsdemand curvedrugoperantpurchase task

Identifiers

PMID42112630
PMCPMC13182549

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.