Evidence map›Paper›PMID 42112583›Full record

ArticleBioMed research international2026

Electroacupuncture-Induced Phrenic Nerve Stimulation for Poststroke Pneumonia: A Propensity Score Matching Analysis.

Bing-Feng Xing, Xiao-Qiang Huang, Hua Zhong, Qi-Fang Liang, Yang Chen, Rui Sun, Wei-Xiong Chen

Abstract read
In one paragraph

Article in BioMed research international, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Bing-Feng XingDepartment of Integrated Traditional Chinese and Western Medicine for Metabolic Diseases, The First Affiliated Hospital of Guangdong Pharmaceutical University, Guangzhou, China, gdpu.edu.cn.ORCID https://orcid.org/0009-0003-4278-4480
Xiao-Qiang HuangDepartment of Integrated Traditional Chinese and Western Medicine for Metabolic Diseases, The First Affiliated Hospital of Guangdong Pharmaceutical University, Guangzhou, China, gdpu.edu.cn.
Hua ZhongPhysical Inspection Section, The First Affiliated Hospital of Guangdong Pharmaceutical University, Guangzhou, China, gdpu.edu.cn.
Qi-Fang LiangDepartment of Integrated Traditional Chinese and Western Medicine for Metabolic Diseases, The First Affiliated Hospital of Guangdong Pharmaceutical University, Guangzhou, China, gdpu.edu.cn.ORCID https://orcid.org/0000-0001-6824-4149
Yang ChenPhysical Inspection Section, The First Affiliated Hospital of Guangdong Pharmaceutical University, Guangzhou, China, gdpu.edu.cn.
Rui SunDepartment of Integrated Traditional Chinese and Western Medicine for Metabolic Diseases, The First Affiliated Hospital of Guangdong Pharmaceutical University, Guangzhou, China, gdpu.edu.cn.
Wei-Xiong ChenDepartment of Integrated Traditional Chinese and Western Medicine for Metabolic Diseases, The First Affiliated Hospital of Guangdong Pharmaceutical University, Guangzhou, China, gdpu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPoststroke pneumonia (PSP) is a common complication in bedridden patients with speech dysfunction, often leading to poor outcomes. This retrospective cohort study explores the clinical efficacy of electroacupuncture (EA) by stimulating the phrenic nerve to improve diaphragmatic activity and treat PSP.

methodsIn this study, 88 hospitalized poststroke patients with pneumonia were divided into two groups. The nonexposure group received standard treatment, including respiratory rehabilitation, whereas the exposure group received additional EA therapy targeting the phrenic nerve. Propensity score matching (PSM) was applied, resulting in 22 patients in the exposure group and 29 in the nonexposure group. Both groups were treated for 2 weeks, during which Clinical Pulmonary Infection Score (CPIS) scores, white blood cell (WBC) count, C-reactive protein (CRP), interleukin-6 (IL-6), and procalcitonin (PCT) levels were measured. In the exposure group, diaphragmatic activity and thickness were also assessed before, during, and after EA.

resultsThe exposure group showed significantly greater improvements compared with the nonexposure group in reducing CPIS scores (mean difference: -1.087; 95% confidence intervals (CIs): -1.68 to -0.494; p < 0.05) and improving inflammatory markers (WBC, CRP, IL-6, and PCT) (p < 0.05 for all comparisons). After PSM, CPIS scores demonstrated a larger absolute reduction in the exposure group compared with controls (-2.32 vs. -1.00), indicating a greater magnitude of clinical improvement. Within the exposure group, diaphragmatic activity improved significantly after 10 days of EA compared with baseline, with significant between-group differences (p < 0.05 for all comparisons). Quantitative assessment further showed that diaphragmatic excursion increased by approximately 0.32 cm following intervention (95% CIs: 0.18-0.46), suggesting enhanced diaphragmatic functional mobility.

conclusionEA may enhance diaphragmatic activity through phrenic nerve stimulation, improving ventilation, sputum clearance, and regulating neuroimmune responses, contributing to the effective management of PSP.

trial registrationInternational Traditional Medicine Clinical Trial Registry: ITMCTR2024000729.

Indexed as

ElectroacupuncturePhrenic NervePneumoniaStrokeAgedAged, 80 and overC-Reactive ProteinDiaphragmFemaleHumansInterleukin-6MaleMiddle AgedPropensity ScoreRetrospective StudiesTreatment OutcomeC-Reactive ProteinInterleukin-6diaphragmatic activityelectroacupuncturephrenic nervepneumoniastroke

Identifiers

PMID42112583
PMCPMC13158868

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.