Evidence map›Paper›PMID 42112515›Full record

ArticleClinical hypertension2026

Modifying effect of statin use on the association between nitrogen dioxide exposure and ischemic heart disease in patients with hypertension.

Hyunji Park, Heeseon Jang, Hokyou Lee, Changsoo Kim, Jaelim Cho

Abstract read
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In one paragraph

Article in Clinical hypertension, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Hyunji ParkDepartment of Public Health, Graduate School, Yonsei University, Seoul, Republic of Korea.ORCID https://orcid.org/0000-0001-7793-554X
Heeseon JangDepartment of Preventive Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea.ORCID https://orcid.org/0000-0002-9737-7220
Hokyou LeeDepartment of Preventive Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea.ORCID https://orcid.org/0000-0002-5034-8422
Changsoo KimDepartment of Preventive Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea.ORCID https://orcid.org/0000-0002-5940-5649
Jaelim ChoDepartment of Preventive Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea.ORCID https://orcid.org/0000-0002-4524-0310

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Air pollution, particularly nitrogen dioxide (NO Methods: A time-stratified case-crossover analysis was conducted using data from National Health Insurance Service for patients hospitalized with IHD in Seoul from 2018 to 2020. The included patients had a prior diagnosis of hypertension and had used antihypertensive medication within the previous 3 years. This group was further stratified as prescription-based statin users and non-users based on whether they had received a statin prescription within 1 year before their IHD admission. The daily average NO Results: Of the 72,753 IHD cases analyzed, 24% were statin non-users and 76% were statin users. A 0.01 ppm increase in NO Conclusions: Short-term NO

Indexed as

Antihypertensive agentsHydroxymethylglutaryl-CoA reductase inhibitorsHypertensionIschemic heart diseaseNitrogen dioxide

Identifiers

PMID42112515
PMCPMC13149958

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.