ReviewCureus2026
Immediate Versus Delayed Breast Reconstruction: Integrating Oncologic Safety, Adjuvant Therapy Considerations, and Aesthetic Outcomes in Multidisciplinary Breast Cancer Care.
Review in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Breast reconstruction has become an integral component of modern breast cancer management, aiming to restore body image and improve the quality of life following mastectomy. The optimal timing of reconstruction remains controversial, particularly in the context of adjuvant therapies such as radiotherapy. The aim of this review is to evaluate current evidence comparing immediate with delayed breast reconstruction, focusing on oncologic safety, interaction with adjuvant therapy, complication profiles, and aesthetic outcomes. A narrative review of the literature was performed, incorporating data from meta-analyses, prospective cohort studies, and multicenter trials assessing outcomes of immediate and delayed breast reconstruction. Immediate breast reconstruction is associated with improved aesthetic outcomes and reduced psychosocial distress while maintaining oncologic safety in appropriately selected patients. Evidence suggests that immediate reconstruction does not increase recurrence rates or negatively affect survival outcomes. However, higher complication rates may be observed, particularly in patients requiring postmastectomy radiotherapy. Delayed reconstruction provides greater flexibility in oncologic management and may reduce complication risk in selected patients, although it is often associated with less favorable aesthetic outcomes. Hybrid approaches such as delayed-immediate reconstruction have emerged to balance these competing considerations. The decision between immediate and delayed breast reconstruction should be individualized within a multidisciplinary framework. The integration of oncologic factors, anticipated adjuvant therapy, and patient preferences is essential to optimize both clinical and aesthetic outcomes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.