ArticleIranian journal of microbiology2026
Burden and resistance of Gram-negative pathogens in ICU-acquired infections in Vietnam: a cross-sectional study.
Article in Iranian journal of microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background and Objectives: This study aimed to describe the burden, pathogen distribution, antimicrobial resistance patterns, and selected clinical outcomes of intensive care unit (ICU)-acquired Gram-negative bacteria (GNB) infections in Vietnam, with exploratory comparative analyses of outcomes. Materials and Methods: A retrospective descriptive study with comparative analyses was conducted among 102 adult patients with culture-confirmed ICU-acquired GNB infections at E Hospital, Hanoi. Demographic, clinical, microbiological, and outcome data were extracted from medical records. Antimicrobial susceptibility testing was performed according to Clinical and Laboratory Standards Institute guidelines. Comparisons between outcome groups were assessed using chi-square test, with effect sizes quantified using Cramer's V. Results: Pneumonia was the predominant infection (70.5%), followed by urinary tract (15.2%) and bloodstream infections (10.6%). GNB accounted for 68.3% of all hospital-acquired infections (HAIs), with Conclusion: GNB dominate ICU-acquired infections in Vietnam and demonstrate alarming antimicrobial resistance, underscoring the urgent need for strengthened infection control and antimicrobial stewardship.
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