ArticleEFSA journal. European Food Safety Authority2012
Scientific Opinion on the safety of stigmasterol-rich plant sterols as food additive.
Article in EFSA journal. European Food Safety Authority, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed.
- Therapeutic potential of phytochemical compounds in cardiovascular disease: a comprehensive review.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2026Review
- Advances and Challenges in Plant Sterol Research: Fundamentals, Analysis, Applications and Production.Molecules (Basel, Switzerland) · 2023Review
- Food-Grade Oleogels: Trends in Analysis, Characterization, and Applicability.Gels (Basel, Switzerland) · 2023Review
- Anti-proliferative potential and oxidative reactivity of thermo-oxidative degradation products of stigmasterol and stigmasteryl esters for human intestinal cells.Scientific reports · 2023Article
- Brassicasterol inhibits hepatitis B virus-associated hepatocellular carcinoma development via suppression of AKT signaling pathway.Infectious agents and cancer · 2023Article
- Health Benefits and Pharmacological Properties of Stigmasterol.Antioxidants (Basel, Switzerland) · 2022Review
- Super-critical fluid extract of Bryonopsis laciniosa (Shivlingi) seeds restores fertility in zebrafish models through revival of cytological and anatomical features.Journal of ovarian research · 2022Article
- Safety of the extension of use of plant sterol esters as a novel food pursuant to Regulation (EU) 2015/2283.EFSA journal. European Food Safety Authority · 2020Article
- Article
- Scientific Opinion on the safety of stigmasterol-rich plant sterols as food additive.EFSA journal. European Food Safety Authority · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The Panel on Food Additives and Nutrient Sources added to Food (ANS) delivers a scientific opinion evaluating the safety of use of stigmasterol-rich plant sterols in ready-to-freeze alcoholic cocktails as a stabiliser. Biological and toxicological data on stigmasterol-rich plant sterols were not provided, but the available data on phytosterols and their esters can be used to evaluate the safety of stigmasterol-rich plant sterols provided that the studies are performed with phytosterol preparations containing also a well-defined percentage of stigmasterol. Less than 5% of dietary phytosterols, phytostanols, and their esters are absorbed by the gastrointestinal tract of rats and human. The metabolic fate of phytosterols and their esters is similar between rats and humans. No evidence of mutagenicity or genotoxicity of phytosterols or phytosterol esters was observed. The Panel concluded that stigmasterol-rich plant sterols are not of concern with respect to genotoxicity. Toxicity studies on phytosterols and phytosterol esters were limited to 90-day subchronic toxicity studies and a 2-generation reproductive toxicity study in rats. No chronic toxicity, carcinogenicity or developmental toxicity studies conducted with phytosterols, phytostanols, and their esters were identified. For adults, mean and 95
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