Evidence map›Paper›PMID 42112123›Full record

ArticleJournal of ginseng research2026

Proteomic profiling reveals the mechanism of ginsenoside synthesis in

Zheng-Wei Liang, Shi-Cheng Tang, Yan Ma, Teng Wang, Zheng Lv, Yan-Hui Guan, Jun-Wen Chen, Ming Zhao, Sheng-Chao Yang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of ginseng research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Zheng-Wei LiangHonghe University, Mengzi, 661100, Yunnan Province, China.
Shi-Cheng TangCollege of Agronomy and Biotechnology / College of Tea Science / The Key Laboratory of Medicinal Plant Biology of Yunnan Province / National Local Joint Engineering Research Center on Germplasm Innovation & Utilization of Chinese Medicinal Materials in Southwestern China, Yunnan Agricultural University, Kunming, 650201, China.
Yan MaCollege of Agronomy and Biotechnology / College of Tea Science / The Key Laboratory of Medicinal Plant Biology of Yunnan Province / National Local Joint Engineering Research Center on Germplasm Innovation & Utilization of Chinese Medicinal Materials in Southwestern China, Yunnan Agricultural University, Kunming, 650201, China.
Teng WangCollege of Agronomy and Biotechnology / College of Tea Science / The Key Laboratory of Medicinal Plant Biology of Yunnan Province / National Local Joint Engineering Research Center on Germplasm Innovation & Utilization of Chinese Medicinal Materials in Southwestern China, Yunnan Agricultural University, Kunming, 650201, China.
Zheng LvCollege of Agronomy and Biotechnology / College of Tea Science / The Key Laboratory of Medicinal Plant Biology of Yunnan Province / National Local Joint Engineering Research Center on Germplasm Innovation & Utilization of Chinese Medicinal Materials in Southwestern China, Yunnan Agricultural University, Kunming, 650201, China.
Yan-Hui GuanCollege of Agronomy and Biotechnology / College of Tea Science / The Key Laboratory of Medicinal Plant Biology of Yunnan Province / National Local Joint Engineering Research Center on Germplasm Innovation & Utilization of Chinese Medicinal Materials in Southwestern China, Yunnan Agricultural University, Kunming, 650201, China.
Jun-Wen ChenCollege of Agronomy and Biotechnology / College of Tea Science / The Key Laboratory of Medicinal Plant Biology of Yunnan Province / National Local Joint Engineering Research Center on Germplasm Innovation & Utilization of Chinese Medicinal Materials in Southwestern China, Yunnan Agricultural University, Kunming, 650201, China.
Ming ZhaoCollege of Agronomy and Biotechnology / College of Tea Science / The Key Laboratory of Medicinal Plant Biology of Yunnan Province / National Local Joint Engineering Research Center on Germplasm Innovation & Utilization of Chinese Medicinal Materials in Southwestern China, Yunnan Agricultural University, Kunming, 650201, China.
Sheng-Chao YangHonghe University, Mengzi, 661100, Yunnan Province, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Methods: The contents of notoginsenoside R1, ginsenosides Rg1, Re, Rb1, and Rd in Results: A total of 7578 proteins were identified, among which 252 differentially expressed proteins (DEPs) were characterized. Specifically, 155 were found to be downregulated, while 93 were upregulated in the comparison of high to low (H/L) ginsenoside content. The DEPs were primarily associated with biological processes, molecular functions, and cellular components, as classified by Gene Ontology. Additionally, Kyoto encyclopedia of genes and genomes pathway enrichment analysis revealed a significant involvement of the ribosomal pathway. Notably, 19 enzymes identified among the DEPs are linked to ginsenoside biosynthesis. Conclusions: This study analyzed the differences in the content of five major ginsenosides in

Indexed as

EnzymeGinsenoside synthesisPanax notoginsengProteomic

Identifiers

PMID42112123
PMCPMC13149910

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.