Evidence map›Paper›PMID 42112074›Full record

ArticleAnnals of pediatric cardiology

Infective endocarditis: Revisiting classical signs of enduring relevance.

Amitkumar Pandey, Praveena N Bhaskaran, Shine Kumar, Navaneetha Sasikumar, Brijesh P Kottayil, Raman Krishna Kumar

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Annals of pediatric cardiology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Amitkumar PandeyDepartment of Pediatric Cardiology, Amrita Institute of Medical Sciences and Research Centre, Kochi, Kerala, India.
Praveena N BhaskaranDepartment of Pediatric Infectious Disease, Amrita Institute of Medical Sciences and Research Centre, Kochi, Kerala, India.
Shine KumarDepartment of Pediatric Cardiology, Amrita Institute of Medical Sciences and Research Centre, Kochi, Kerala, India.
Navaneetha SasikumarDepartment of Pediatric Cardiology, Amrita Institute of Medical Sciences and Research Centre, Kochi, Kerala, India.
Brijesh P KottayilDepartment of Pediatric CVTS, Amrita Institute of Medical Sciences and Research Centre, Kochi, Kerala, India.
Raman Krishna KumarDepartment of Pediatric Cardiology, Amrita Institute of Medical Sciences and Research Centre, Kochi, Kerala, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 17-year-old previously healthy girl presented with 7 days of fever and classical peripheral findings including Osler's nodes, Janeway lesions, splinter hemorrhages, and Roth's spots. Echocardiography revealed a large vegetation attached to the posterior mitral leaflet. Blood culture later grew methicillin-sensitive Staphylococcus aureus. Despite antibiotic therapy, the vegetation increased in size with splenic embolization, requiring urgent mitral valve replacement. This case highlights the enduring diagnostic value of classical clinical signs, now rarely seen in high-income settings but still encountered in resource-limited regions, and emphasizes the importance of early echocardiographic evaluation in such presentations.

Indexed as

Infective endocarditisJaneway lesionsOsler’s nodesRoth spotssplenic infarctsplinter hemorrhage

Identifiers

PMID42112074
PMCPMC13152097

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.