ArticleOpen forum infectious diseases2026
Low Yield of Blood Cultures After End of Therapy of an Episode of Infective Endocarditis: 12 Years' Experience From a Referral Center.
Article in Open forum infectious diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Infective endocarditis (IE) carries a significant risk of recurrence. European clinical guidelines recommend performing follow-up blood cultures (BCs), although evidence regarding their utility is limited. We aimed to assess the yield of follow-up BCs in these patients. Methods: Single-center post hoc analysis of a prospective cohort including IE survivors diagnosed between 2012 and 2023 with at least 12 months of follow-up. Results: Among 225 patients included, follow-up BCs were performed in 153 (68.0%). Recurrence was diagnosed in 19 patients (8.4%). Patients with recurrence had higher mortality during follow-up (15.8% vs 4.4%, Conclusions: Follow-up BC after an IE episode appears to have low utility, with similar rates of true positives and contaminants. Patients with follow-up BCs did not have more recurrences diagnosed or lower mortality during follow-up.
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