Evidence map›Paper›PMID 42111815›Full record

SynthesisPeerJ2026

Therapeutic use of highly concentrated CO

Shaodong Chen, Jia Ying Tong, Muhammad Shahzad Aslam

Abstract readSystematic ReviewMeta-Analysis
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in PeerJ, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Shaodong Chen *School of Traditional Chinese Medicine, Xiamen University Malaysia, Jalan Sunsuria, Bandar Sunsuria, Selangor, Malaysia.
Jia Ying TongSchool of Traditional Chinese Medicine, Xiamen University Malaysia, Jalan Sunsuria, Bandar Sunsuria, Selangor, Malaysia.
Muhammad Shahzad Aslam *Department of Traditional Chinese Medicine, School of Medicine, Xiamen University, Xiamen, Fujian, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Wound healing poses a persistent clinical challenge, especially in chronic wounds like diabetic foot ulcers and pressure injuries. Highly concentrated carbon dioxide (CO Objective: To evaluate the efficacy of highly concentrated CO Methods: This systematic review and meta-analysis followed PRISMA guidelines and was registered in PROSPERO (CRD420251035698). Six databases were searched, identifying 10,348 records. Five randomized controlled trials met the inclusion criteria, involving participants with wounds treated using highly concentrated CO Results: Five trials ( Conclusion: Highly concentrated CO

Indexed as

BathsCarbon DioxideDiabetic FootWound HealingHumansRandomized Controlled Trials as TopicCarbon DioxideCarbon dioxide therapyChronic woundsDiabetic foot ulcerMeta-analysisPressure ulcerRandomized controlled trialWound healing

Identifiers

PMID42111815
PMCPMC13155233

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.