Evidence map›Paper›PMID 42111509›Full record

ArticleThe Pan African medical journal2026

Effect of khat

Ahmed Ismail Mohamed, Jama Mohamed, Mustafe Mohamed Hussien, Hussein Mohamoud Nour, Abdulahi Abdiwali Mahamed, Ahmed Ibrahim Farah

Abstract readComparative Study
In one paragraph

Article in The Pan African medical journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ahmed Ismail MohamedFaculty of Human Nutrition and Dietetics, College of Medicine and Health Science, University of Hargeisa, Hargeisa, Somaliland.
Jama MohamedFaculty of Medical Laboratory Science, College of Medicine and Health Science, University of Hargeisa, Hargeisa, Somaliland.
Mustafe Mohamed HussienSchool of Medical Laboratory Science, Edna Adan University, Hargeisa, Somaliland.
Hussein Mohamoud NourFaculty of Data Science and Statistics, College of Business, Economy, and Statistics, University of Hargeisa, Hargeisa, Somaliland.
Abdulahi Abdiwali MahamedDepartment of Nutrition, College of Health Science, Admas University, Garowe, Somalia.
Ahmed Ibrahim FarahFaculty of Medical Laboratory Science, College of Medicine and Health Science, University of Hargeisa, Hargeisa, Somaliland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: khat (Catha edulis) chewing is a prevalent practice in Somaliland, yet its impact on liver function among metabolically healthy males remains inadequately understood. This study aims to evaluate the effects of chronic khat chewing on liver function markers in the Somaliland population. Methods: a comparative cross-sectional study was conducted in Somaliland from January to March, 2024. A sample of apparently healthy males, consisting of habitual khat chewers and non-chewers, was selected using purposive sampling and convenience sampling techniques, respectively. Liver function markers analyzed included total bilirubin, total protein, albumin, and glutamate pyruvate transaminase (GPT). Data were analyzed using descriptive statistics and inferential tests to compare the two groups, with significance set at p < 0.05. Results: chronic khat chewers exhibited higher total bilirubin levels (p = <0.001) and lower total protein levels (p = <0.001) compared to non-chewers, suggesting potential hepatotoxic effects. No significant differences were observed in the serum levels of albumin and GPT between the two groups. Conclusion: chronic khat chewing is associated with significant alterations in liver function markers, particularly elevated total bilirubin and reduced total protein levels, indicating potential hepatotoxic effects. However, albumin and GPT levels remained unaffected. Public health authorities should implement educational campaigns to raise awareness about the potential adverse effects of Khat on liver health. Healthcare providers should consider monitoring liver function markers in habitual Khat chewers as part of routine health assessments.

Indexed as

CathaLiverAdultAlanine TransaminaseBilirubinBiomarkersCross-Sectional StudiesHumansLiver Function TestsMaleMasticationMiddle AgedYoung AdultAlanine TransaminaseBilirubinBiomarkersbiochemical markersKhat chewingliver function markers

Identifiers

PMID42111509
PMCPMC13156015

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.