ArticleHealth science reports2026
Investigating Novel Inflammatory Indices and Their Links to Mortality, Cancer, and Cardiovascular Disease: A 10-Year Cohort Study.
Article in Health science reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Investigating Novel Inflammatory Indices and Their Links to Mortality, Cancer, and Cardiovascular Disease: A 10-Year Cohort Study.Health science reports · 2026Article
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background and Aims: Inflammatory indices, including neutrophil-to-lymphocyte-platelet ratio (NLPR), systemic immune-inflammation index (SII), platelet-to-lymphocyte ratio (PLR), and neutrophil-to-lymphocyte ratio (NLR) have been proposed as prognostic markers for mortality. This study explored the links between novel inflammatory markers and mortality, including all-cause death, cancer, and cardiovascular disease (CVD). Methods: The MASHAD cohort study included adults aged 35-65 years through a stratified cluster sampling method. Demographic, health-related, and inflammatory indices data were collected at baseline. Participants were followed for 10 years. Cox regression and Kaplan-Meier survival analyses were employed to examine the associations of inflammatory markers with mortality outcomes. Results: In unadjusted analyses, NLPR in the highest tertile (≥ 0.035) was associated with increased risks of all-cause mortality (HR = 1.43; 95% CI: 1.10-1.88; Conclusion: PLR and NLPR have potential as prognostic markers for all-cause mortality, with PLR demonstrating a consistent protective effect at moderate levels. Further research with extended follow-up periods is necessary to confirm these results and investigate their potential relevance to clinical practice.
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