Trans-arterial gemcitabine micro perfusion of locally advanced pancreatic cancer enabled by coil plus glue embolization of a pancreaticoduodenal branch.

Bela Kis, Olivia Bishop, Elias Salloum, Mustafa Al-Roubaie, Dae Won Kim, Ramtin Agah

Abstract readCase Reports

In one paragraph

Article in Radiology case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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6 authors.

Bela KisDiagnostic Imaging and Interventional Radiology, Moffitt Cancer Center, Tampa, FL, United States.

Olivia BishopDiagnostic Imaging and Interventional Radiology, Moffitt Cancer Center, Tampa, FL, United States.

Elias SalloumDiagnostic Imaging and Interventional Radiology, Moffitt Cancer Center, Tampa, FL, United States.

Mustafa Al-RoubaieDiagnostic Imaging and Interventional Radiology, Moffitt Cancer Center, Tampa, FL, United States.

Dae Won KimGastrointestinal Oncology, Moffitt Cancer Center, Tampa, FL, United States.

Ramtin AgahRenovoRx, Inc., Los Altos, CA, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Trans-arterial micro perfusion (TAMP) is a technique that utilizes a novel double-balloon occlusion catheter (RenovoCath) for localized drug delivery in the absence of tumor feeder vessels. Side branch exclusion is a prerequisite for achieving the intra-arterial pressure that drives TAMP. We report a case in which coil plus glue embolization of a vessel side branch successfully enabled TAMP-mediated drug delivery. An 82-year-old male with locally advanced pancreatic cancer was referred for gemcitabine treatment via TAMP. Angiography identified the superior mesenteric artery (SMA) as the best target; however, a pancreaticoduodenal artery (PDA) branch of the SMA could not be excluded. Complete occlusion of the PDA branch was achieved with coil plus glue embolization; TAMP-mediated gemcitabine delivery was then successfully performed in the same setting. In cases where arterial anatomy may otherwise preclude TAMP, coil plus glue embolization of side branches may provide a viable solution.

Indexed as

Arterial embolizationChemoperfusionLocally advanced pancreatic cancerTrans-arterial micro perfusion

Identifiers

PMID42111415

DOI10.1016/j.radcr.2026.04.043

PMCPMC13156556

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