ArticleRadiology case reports2026
Atypical presentation of intraosseous plasmacytoma in a patient with POEMS syndrome.
Article in Radiology case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
POEMS syndrome is an uncommon paraneoplastic syndrome featuring polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes. POEMS syndrome in conjunction with plasmacytoma is a particularly rare finding, mostly featured only in case reports and small case series. We present a case of a 52-year-old female with POEMS syndrome with a biopsy-proven solitary bone plasmacytoma of the scapula demonstrating atypical imaging features. While plasmacytomas are typically considered locally aggressive lesions, the plasmacytoma in this patient with POEMS syndrome exhibited stability in size and local invasion over a period of almost a year despite lack of treatment. This case demonstrates that radiographic stability of these lesions, while uncommon, can occur and should not exclude the diagnosis of plasmacytoma.
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