Evidence map›Paper›PMID 42111369›Full record

ArticleACG case reports journal2026

Perplexing Severe Cholestasis in the Postpartum Period.

Sarah Yosief, Wei Chen, Kimberly Wescoe, M S Branch, Mustafa Bashir, Kara Wegermann

Abstract readCase Reports
In one paragraph

Article in ACG case reports journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sarah YosiefDepartment of Medicine, Duke University Medical Center, Durham, NC.
Wei ChenDepartment of Pathology, Duke University Medical Center, Durham, NC.
Kimberly WescoeDepartment of Medicine, Division of Gastroenterology, Duke University Medical Center, Durham, NC.
M S BranchDepartment of Medicine, Division of Gastroenterology, Duke University Medical Center, Durham, NC.
Mustafa BashirDepartments of Radiology and Medicine, Duke University Medical Center, Durham, NC.
Kara WegermannDepartment of Medicine, Division of Gastroenterology, Duke University Medical Center, Durham, NC.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 36-year-old postpartum woman with prior intrahepatic cholestasis of pregnancy and gallstone pancreatitis presented with right upper quadrant pain, jaundice, and elevated liver enzymes. Initial workup suggested drug-induced liver injury, but laboratory results worsened after antibiotics were discontinued. Imaging and liver biopsies revealed cholestasis and progressive fibrosis. Endoscopic retrograde cholangiopancreatography finally confirmed primary sclerosing cholangitis, though overlap with pregnancy-related liver conditions delayed diagnosis. This case highlights the diagnostic challenges of postpartum cholestasis and illustrates how primary sclerosing cholangitis may emerge in temporal association with pregnancy despite initially nondiagnostic imaging and histology.

Indexed as

cholestatic liver diseasecirrhosisdrug-induced liver injuryendoscopic retrograde cholangiopancreatographyintrahepatic cholestasis of pregnancypostpartum cholestasisprimary sclerosing cholangitis

Identifiers

PMID42111369
PMCPMC13152223

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.