Evidence map›Paper›PMID 42111338›Full record

ArticleAdvanced synthesis & catalysis2025

Dual NHC/HAT-Promoted Esterification to Access α-Aryl Glycines.

Matthew J McGill, Adam X Wayment, Cullen R Schull, Karl A Scheidt

Abstract read
In one paragraph

Article in Advanced synthesis & catalysis, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. α-C-H Functionalization of Benzylamines: A Crucial Yet Challenging Transformation.Chemistry (Weinheim an der Bergstrasse, Germany) · 2026
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Matthew J McGillDepartment of Chemistry, Northwestern University, Silverman Hall, Evanston, Illinois 60208, USA.
Adam X WaymentDepartment of Chemistry, Northwestern University, Silverman Hall, Evanston, Illinois 60208, USA.
Cullen R SchullDepartment of Chemistry, Northwestern University, Silverman Hall, Evanston, Illinois 60208, USA.
Karl A ScheidtDepartment of Chemistry, Northwestern University, Silverman Hall, Evanston, Illinois 60208, USA.

Funding

New Cooperative Catalysis Concepts for Asymmetric SynthesisR35GM136440 · NIGMS · NORTHWESTERN UNIVERSITY · PI Karl A Scheidt · 2020 to 2026
$2.9M
NIGMS NIH HHS R35 GM136440
6 · The paper itself

Abstract

α-aryl glycines are among the most important carbonyl compounds, particularly as nonproteinogenic α-amino acids present in many pharmacophores. As such, many strategies have been developed to access this motif, but direct carboxylation methods remain underdeveloped. Herein, we employ a dual NHC/HAT catalysis strategy to access 2-azaallyl radicals, which subsequently couple with

Indexed as

alpha-amino radicalesterificationhydrogen atom transferN-heterocyclic carbeneorganophotocatalyst

Identifiers

PMID42111338
PMCPMC13155416

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.