ReviewBrain circulation
Progress on the mechanism of pathological injury secondary to venous stroke and their therapeutic strategies: A narrative review.
Review in Brain circulation. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Intracranial venous thrombosis imaging by anatomical location: an educational review with mimics and diagnostic pitfalls.Insights into imaging · 2026Article
- Clinical presentation domains and venous anatomical patterns in cerebral venous thrombosis: a retrospective cohort study.BMC neurology · 2026Observational
- Meningeal lymphatic vessel dysfunction exacerbates brain injury in CVST mice via endoplasmic reticulum and oxidative stress pathways.Frontiers in immunology · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cerebral venous thrombosis (CVT) is a subset of stroke with a rising trend over the recent years, namely, venous stroke. Its pathogenesis is distinctly heterogeneous from that of arterial ischemic stroke. Severe CVT often results in irreversible brain damage due to concomitant cerebral venous infarction and/or hemorrhage, and the prognosis is extremely poor. Currently, venous stroke has received increasing attention and focus from the scientific community. It has been identified that blood-brain barrier disruption, impaired lymphatic drainage, immune inflammatory response, endoplasmic reticulum stress, oxidative/nitrative stress, and excitotoxicity are intimately tied to the pathophysiology secondary to CVT; however, the specific pathological molecular mechanisms remain to be elaborated in detail. Based on the latest research, combined with the current transcriptomics data, this study reviews the potential pathomechanisms linked with secondary brain injury post-CVT and summarizes the relevant therapeutic strategies, which will contribute to the grasp of the pathology of venous stroke for early clinical recognition and intervention.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.