Evidence map›Paper›PMID 42111270›Full record

ReviewFrontiers in cell and developmental biology2026

Stage-dependent endoplasmic reticulum homeostasis in osteogenic differentiation.

Jili Wang, Xiaoyu Li, Xiaoge Wang, Linyi Wang, Yandong Zhang, Xiaokun Dong, Xiangpeng Lu, Shangzeng Wang

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in cell and developmental biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jili Wang *The Second Affiliated Hospital of Henan University of Chinese Medicine, Zhengzhou, China.
Xiaoyu Li *The Second Affiliated Hospital of Henan University of Chinese Medicine, Zhengzhou, China.
Xiaoge Wang *Henan University of Chinese Medicine, Zhengzhou, China.
Linyi WangHenan University of Chinese Medicine, Zhengzhou, China.
Yandong ZhangLuohe Medical College, Luohe, China.
Xiaokun DongHenan University of Chinese Medicine, Zhengzhou, China.
Xiangpeng LuThe first Affiliated Hospital of Henan University of Chinese Medicine, Zhengzhou, China.
Shangzeng WangThe Second Affiliated Hospital of Henan University of Chinese Medicine, Zhengzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Osteoporosis (OP) is primarily characterized by reduced bone mass, microarchitectural deterioration, and an increased susceptibility to fragility fractures. A central pathological feature of OP is the progressive impairment of osteogenic differentiation and bone matrix production in osteoblasts. The endoplasmic reticulum (ER), a pivotal organelle responsible for secretory protein folding, lipid/sterol biosynthesis, and intracellular Ca

Indexed as

calcium homeostasisendoplasmic reticulum stressER-phagylipid metabolismosteogenic differentiation

Identifiers

PMID42111270
PMCPMC13149409

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.