ArticleFrontiers in cell and developmental biology2026
Evidence for murine cutaneous immune surveillance localized to hair follicle epithelium.
Article in Frontiers in cell and developmental biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Epithelial expression of the gene encoding the anti-microbial peptide PGRP-S was previously found to be specifically associated with M cells in mucosal epithelium. However, recent studies have found PGRP-S expression by a variety of epithelia not providing direct M cell-like microparticle transcytosis into lymphoid tissues. Thus, in mouse epidermis we found that PGRP-S expression, revealed by a dsRed reporter, was specific to subsets of hair follicle epithelium, depending on the specific skin region, and not associated with lymphoid aggregates. Interestingly, expression in flank skin hair follicle epithelium was also transiently inducible upon exposure to a suspension of
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