ArticleiScience2026
Enabling adaptability and hydraulic resistance in minimally invasive glaucoma surgery using an architecture-driven approach.
Article in iScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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0 citing papers in PubMed.
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To address primary open-angle glaucoma, we introduce an architecture-driven design approach for developing minimally invasive glaucoma surgery devices. By tailoring the micro- and macro-architecture of shape memory alloys (SMAs), guided by theoretical and numerical modeling, we transformed an initially stiff metallic structure into a flexible, deployable microstent that conforms to soft tissue while maintaining controlled hydraulic resistance. This approach enables the microstent to self-expand upon deployment, forming an artificial fistula between the anterior chamber and the subconjunctival space to facilitate aqueous humor drainage and lower intraocular pressure (IOP).
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.