Evidence map›Paper›PMID 42111188›Full record

ArticleiScience2026

Integrated multiomics reveals starvation-driven keratin degradation and persistence in

Jae-Yoon Sung, Ji-Yeon Kim, Hyeon-Su Jin, Je-Hyun Baek, Nicole Enjeh Kim, Hyun Ho Song, Seong-Hun Bong, Yong-Jik Lee, Byoung-Chan Kim, Do Yup Lee and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in iScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jae-Yoon SungDepartment of Biotechnology, Yonsei University, Seoul 03722, South Korea.
Ji-Yeon KimDepartment of Environment and Energy Engineering, Gwangju Institute of Science and Technology (GIST), Gwangju 61005, South Korea.
Hyeon-Su JinDepartment of Biotechnology, Yonsei University, Seoul 03722, South Korea.
Je-Hyun BaekR&D Center for Clinical Mass Spectrometry, Seegene Medical Foundation, Seoul 04805, South Korea.
Nicole Enjeh KimDepartment of Biotechnology, Yonsei University, Seoul 03722, South Korea.
Hyun Ho SongDepartment of Agricultural Biotechnology, Center for Food and Bioconvergence, Research Institute for Agricultural and Life Sciences, Seoul National University, Seoul 08826, South Korea.
Seong-Hun BongDepartment of Agricultural Biotechnology, Center for Food and Bioconvergence, Research Institute for Agricultural and Life Sciences, Seoul National University, Seoul 08826, South Korea.
Yong-Jik LeeDepartment of Bio-Cosmetics, Seowon University, Cheongju 28674, South Korea.
Byoung-Chan KimHealthBiome, Inc., 48, Yuseong-daero 1184beon-gil, Yuseong-gu, Daejeon 34109, South Korea.
Do Yup LeeDepartment of Agricultural Biotechnology, Center for Food and Bioconvergence, Research Institute for Agricultural and Life Sciences, Seoul National University, Seoul 08826, South Korea.
Dong-Woo LeeDepartment of Biotechnology, Yonsei University, Seoul 03722, South Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Keratin is one of the most recalcitrant biopolymers due to its dense disulfide crosslinks; yet, how microbial keratin degradation is regulated under nutrient limitation remains poorly understood. Here, we integrated time-resolved transcriptomics, proteomics, and metabolomics to investigate starvation-driven keratin utilization in the extremophilic bacterium

Indexed as

biological sciences

Identifiers

PMID42111188
PMCPMC13157175

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.