Evidence map›Paper›PMID 42111178›Full record

ArticleiScience2026

An improved method for high-purity isolation of oligodendrocytes from neonatal and adult mouse brain.

Peiyi Guo, Elisabet Mandon, Jie Wang, Morgan Mooney, Keith Reddig, Paula Vo, Madison C Jerome, Anoushka Lotun, Jessica B Spinelli, Guangping Gao and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in iScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Peiyi GuoDepartment of Genetic and Cellular Medicine, University of Massachusetts Chan Medical School, Worcester, MA, USA.
Elisabet MandonRNA Therapeutics Institute, University of Massachusetts Chan Medical School, Worcester, MA, USA.
Jie WangCollege of Life Science, Nanjing Normal University, Nanjing, China.
Morgan MooneyDepartment of Genetic and Cellular Medicine, University of Massachusetts Chan Medical School, Worcester, MA, USA.
Keith ReddigElectron Microscopy Facility, Department of Radiology, University of Massachusetts Chan Medical School, Worcester, MA, USA.
Paula VoProgram in Molecular Medicine, University of Massachusetts Chan Medical School, Worcester, MA, USA.
Madison C JeromeProgram in Molecular Medicine, University of Massachusetts Chan Medical School, Worcester, MA, USA.
Anoushka LotunDepartment of Genetic and Cellular Medicine, University of Massachusetts Chan Medical School, Worcester, MA, USA.
Jessica B SpinelliHoward Hughes Medical Institute, Program in Molecular Medicine, University of Massachusetts Chan Medical School, Worcester, MA, USA.
Guangping GaoDepartment of Genetic and Cellular Medicine, University of Massachusetts Chan Medical School, Worcester, MA, USA.
Dominic J GesslerDepartment of Genetic and Cellular Medicine, University of Massachusetts Chan Medical School, Worcester, MA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oligodendrocytes are central to myelination and are key targets in myelin disease research and gene therapy. We optimized magnetic isolation of O4

Indexed as

biological sciences research methodologiescell biologyneuroscience

Identifiers

PMID42111178
PMCPMC13157168

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.