ArticleJournal of the Society for Cardiovascular Angiography & Interventions2026
Sex-Based Outcomes in Patients With High Bleeding Risk After PCI With 1-Month DAPT: Results From the Onyx ONE Clear Study.
Article in Journal of the Society for Cardiovascular Angiography & Interventions, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Can DAPT Be Safely Shortened to 1 Month After Bifurcation PCI in High Bleeding Risk Patients? Lessons From Onyx ONE Clear.Journal of the Society for Cardiovascular Angiography & Interventions · 2026Article
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Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: The Onyx ONE Clear study demonstrated favorable 1-year efficacy and safety outcomes in patients with high bleeding risk (HBR) and 1 month of event-free dual antiplatelet therapy (DAPT) after treatment with Resolute Onyx zotarolimus-eluting stents (ZES). Differences in outcomes after early DAPT discontinuation by sex have not been fully defined. Methods: Eligible patients had ≥1 HBR criterion and underwent percutaneous coronary intervention with the Resolute Onyx ZES. Outcomes were evaluated in patients "clear" of 30-day adverse events. The primary end point was a composite of cardiac death or myocardial infarction (CD/MI). Bleeding and ischemic outcomes at 2 years were compared by sex in this prespecified subgroup analysis. Results: Among 1507 patients included, 32.2% were women. Women were older and more likely to present with acute coronary syndrome. The 2-year rates of CD/MI were 10.6% in women vs 12.6% in men ( Conclusions: In HBR patients treated with Resolute Onyx ZES and 1-month abbreviated DAPT, rates of CD or MI at 2 years were low, with no significant sex-related differences in ischemic and bleeding events. These data support the use of abbreviated DAPT after ZES in women and men with HBR.
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