Evidence map›Paper›PMID 42111072›Full record

ArticleFrontiers in neurology

Impact of anesthesia methods on functional outcomes in patients with acute ischemic stroke undergoing mechanical thrombectomy: insights from the ENCHANTED2/MT trial.

Hao Wang, Hongye Xu, Xiongfeng Wu, Xiaoxi Zhang, Rundong Chen, Lei Zhang, Xiaofei Ye, Yongwei Zhang, Pengfei Yang, Shengdong Chen and 2 more

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Article in Frontiers in neurology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

12 authors.

Hao Wang *Department of Neurology, Linyi People's Hospital, Affiliated Hospital of Shandong Second Medical University, Linyi, China.
Hongye Xu *Neurovascular Center, Changhai Hospital, Naval Medical University, Shanghai, China.
Xiongfeng Wu *Neurovascular Center, Changhai Hospital, Naval Medical University, Shanghai, China.
Xiaoxi ZhangNeurovascular Center, Changhai Hospital, Naval Medical University, Shanghai, China.
Rundong ChenNeurovascular Center, Changhai Hospital, Naval Medical University, Shanghai, China.
Lei ZhangNeurovascular Center, Changhai Hospital, Naval Medical University, Shanghai, China.
Xiaofei YeDepartment of Statistics, Naval Medical University, Shanghai, China.
Yongwei ZhangNeurovascular Center, Changhai Hospital, Naval Medical University, Shanghai, China.
Pengfei YangNeurovascular Center, Changhai Hospital, Naval Medical University, Shanghai, China.
Shengdong ChenNo. 904 Hospital of the PLA Joint Logistics Support Force, Wuxi, China.
Xin YouDepartment of Health Management Center, Linyi People's Hospital, Affiliated Hospital of Shandong Second Medical University, Shandong, China.
Jianmin LiuNeurovascular Center, Changhai Hospital, Naval Medical University, Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The choice of anesthesia modality during mechanical thrombectomy (MT) for acute ischemic stroke remains debated. This study aimed to analyze the impact of anesthesia type on clinical outcomes following endovascular therapy (EVT). Methods: This subgroup analysis of the ENCHANTED2/MT trial included patients with large vessel occlusion (LVO) acute ischemic stroke who achieved successful reperfusion (eTICI ≥2b). Patients were stratified by anesthesia type: general anesthesia (GA) or non-general anesthesia (Non-GA). The primary outcome was functional recovery, assessed by the distribution of scores on the modified Rankin Scale (mRS; range 0 [no symptoms] to 6 [death]) at 90 days. Efficacy was analyzed using ordinal logistic regression. Results: A total of 809 patients were included (GA: 344; Non-GA: 465). There was no significant between-group difference in the primary outcome of mRS score distribution. The incidence of postoperative pneumonia was significantly lower in the Non-GA group (adjusted odds ratio [aOR] 0.33, 95% CI 0.14-0.74; Conclusion: In patients undergoing mechanical thrombectomy for acute ischemic stroke, Non-GA may be associated with better functional outcomes in patients presenting with milder neurological deficits. GA was associated with an increased risk of postoperative pneumonia.

Indexed as

acute ischaemic strokeanesthesia modalityendovascular thrombectomyfunctional independencerandomized trial

Identifiers

PMID42111072
PMCPMC13149095

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.