ArticleFrontiers in neurology
Vestibular recovery and central compensation after acute unilateral vestibulopathy - changes in saccadic response patterns and gains over time.
Article in Frontiers in neurology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Article
- Multiple sclerosis as an under-recognized cause of acute vertigo: clinical and pathophysiologic insights.Frontiers in neurology · 2026Review
- The clinical value of vHIT saccadic parameters in the diagnosis and management of central vestibular disorders: a narrative review.Frontiers in neurologyReview
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Acute unilateral vestibulopathy (AUVP), or vestibular neuritis, disrupts the vestibulo-ocular reflex (VOR), leading to impaired gaze stability during head movements. Vestibular function typically recovers to some extent. However, if recovery is incomplete, corrective eye saccades must compensate for the deficient VOR function. The aim was to analyze the progression of VOR gain recovery and development of different corrective eye saccade patterns after AUVP. Methods: A prospective longitudinal study was performed, including 43 patients with AUVP, that were examined using the video head impulse test (vHIT) during the first week after symptom onset and after 1 month, 3 months, and 12 months. Data collected included ipsilesional and contralesional gain recovery and the presence of covert and overt saccades. Results: Both ipsilesional (p < 0.001) and contralesional (p ≤ _0.038) VOR gain improved significantly over 12 months, with the most pronounced recovery occurring within the first 3 months ( Discussion: VOR recovery manifests with variable patterns. The degree of VOR gain deficit appears to drive the specific type of compensatory saccade patterns employed. Unilateral vestibular impairment may result in bilateral overt saccades, whereas bilateral covert saccades are rarely observed. The presence of covert saccades is a strong indicator of significant underlying VOR hypofunction.
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