ReviewNeuro-oncology practice2026
Corticosteroid use in pediatric neuro-oncology symptom management: A rapid review.
Review in Neuro-oncology practice, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Corticosteroids are used routinely in pediatric patients with central nervous system tumors. However, the efficacy profiles of these medications, prevalence of adverse effects, dosing schedules, and impact on patients' quality-of-life are poorly elucidated. The aim of this study was to identify, appraise, and synthesize available international evidence regarding the role of corticosteroids in the symptom management of pediatric neuro-oncology patients. Methods: A rapid review of articles studying the role of corticosteroids in pediatric neuro-oncology was undertaken in August 2024. This study is reported using the PRISMA statement and was registered with PROSPERO (CRD42024567489). Five databases were searched, and data were analyzed using narrative synthesis. Results: Of the 1935 identified papers, 9 met the inclusion criteria ( Conclusion: As the first review utilizing systematic methodology exploring the topic of corticosteroid use in pediatric neuro-oncology, we identified a paucity of pediatric studies addressing corticosteroid efficacy. Dosing is variable, adverse effects are duration-dependent and multi-system and there is an urgent need for the development of guidelines to inform best practice. High-income countries and inpatient perioperative settings dominate the published literature. There is an absence of consumer voices addressing the impact on quality-of-life from corticosteroid use.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.