Evidence map›Paper›PMID 42111003›Full record

ArticleBiomedical optics express2026

Biodegradable and biocompatible poly(lactic acid) optical fibers for fiber-guided photothermal therapy of breast cancer cells in vitro.

Shengli Pan, Shuyuan Zhu, Li Chen, Yiqian Fu, Jingyuan Yao, Bo Liu, Tao Ye, Chris Zhou, Orlando J Rojas, Xin Lu and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomedical optics express, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Shengli PanBeijing Engineering Research Center of Laser Technology, Beijing University of Technology, Beijing, 100124, China.
Shuyuan ZhuBeijing Engineering Research Center of Laser Technology, Beijing University of Technology, Beijing, 100124, China.
Li ChenBeijing Engineering Research Center of Laser Technology, Beijing University of Technology, Beijing, 100124, China.
Yiqian FuBeijing Engineering Research Center of Laser Technology, Beijing University of Technology, Beijing, 100124, China.
Jingyuan YaoBeijing Engineering Research Center of Laser Technology, Beijing University of Technology, Beijing, 100124, China.
Bo LiuBeijing Engineering Research Center of Laser Technology, Beijing University of Technology, Beijing, 100124, China.
Tao YeBeijing Engineering Research Center of Laser Technology, Beijing University of Technology, Beijing, 100124, China.
Chris ZhouBioproducts Institute, The University of British Columbia, 2360 East Mall, Vancouver, BC V6 T 1Z3, Canada.
Orlando J RojasBioproducts Institute, The University of British Columbia, 2360 East Mall, Vancouver, BC V6 T 1Z3, Canada.
Xin LuBioproducts Institute, The University of British Columbia, 2360 East Mall, Vancouver, BC V6 T 1Z3, Canada.
Xiuhong WangBeijing Engineering Research Center of Laser Technology, Beijing University of Technology, Beijing, 100124, China.
Pu WangBeijing Engineering Research Center of Laser Technology, Beijing University of Technology, Beijing, 100124, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Breast cancer remains one of the leading causes of cancer-related mortality among women worldwide, while conventional clinical treatments are often limited by high invasiveness, severe side effects, and insufficient spatial control over therapeutic energy delivery. Fiber-based optical platforms offer a compelling strategy for minimally invasive photothermal therapy by enabling precise and localized light transmission within biological tissues. Here, we report a scalable extrusion-thermal drawing strategy for fabricating biodegradable and biocompatible poly(lactic acid)-based optical fibers (BPOFs) and demonstrate their application as biodegradable optical waveguides for fiber-mediated photothermal ablation of breast cancer cells. Owing to the intrinsic biodegradability and biosafety of poly(lactic acid), the resulting BPOFs exhibit excellent structural uniformity, mechanical flexibility, and efficient near-infrared light guidance, with a low propagation loss of 0.33 dB cm

Identifiers

PMID42111003
PMCPMC13155836

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.