Evidence map›Paper›PMID 42110975›Full record

ArticleJBMR plus2026

Wnt5a gain- and loss-of-function in bone have distinct craniofacial phenotypes.

Claire J Houchen, Portia Hahn Leat, Cassandra Delich, Jocelyn Vang, Sara Yingling-Haggard, Joseph L Roberts, Hicham Drissi, Erin E Bumann

Abstract read
In one paragraph

Article in JBMR plus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Claire J HouchenSchool of Dentistry, University of Missouri-Kansas City, Kansas City, MO 64108, United States.ORCID https://orcid.org/0000-0002-2003-4625
Portia Hahn LeatSchool of Dentistry, University of Missouri-Kansas City, Kansas City, MO 64108, United States.
Cassandra DelichSchool of Dentistry, University of Missouri-Kansas City, Kansas City, MO 64108, United States.ORCID https://orcid.org/0009-0009-9109-2839
Jocelyn VangSchool of Dentistry, University of Missouri-Kansas City, Kansas City, MO 64108, United States.ORCID https://orcid.org/0000-0001-6839-1173
Sara Yingling-HaggardSchool of Dentistry, University of Missouri-Kansas City, Kansas City, MO 64108, United States.
Joseph L RobertsEmory School of Medicine, Emory University, Atlanta, GA 30322, United States.
Hicham DrissiEmory School of Medicine, Emory University, Atlanta, GA 30322, United States.ORCID https://orcid.org/0000-0002-3322-281X
Erin E BumannSchool of Dentistry, University of Missouri-Kansas City, Kansas City, MO 64108, United States.ORCID https://orcid.org/0000-0002-8698-7808

Funding

Wnt5a/Ror2 Signaling in Jaw Bone DevelopmentR03DE031388 · NIDCR · UNIVERSITY OF MISSOURI KANSAS CITY · PI BUMANN, ERIN EALBA · 2021 to 2023
$390k
Bone anabolic effects of osteoclast-produced phospho-Wnt5aR56AR080718 · NIAMS · EMORY UNIVERSITY · PI DRISSI, MOULAY HICHAM · 2023 to 2023
$313k
NIAMS NIH HHS R56 AR080718NIDCR NIH HHS R03 DE031388
6 · The paper itself

Abstract

Robinow syndrome has characteristic craniofacial and dental features and can be caused by gain- or loss-of-function variants in Wnt family member 5A (

Indexed as

apoptosiscraniofacial abnormalitiesfacial asymmetrymandibular condylemicrognathismRobinow syndrometooth eruption

Identifiers

PMID42110975
PMCPMC13156483

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.