Evidence map›Paper›PMID 42110974›Full record

ArticleJBMR plus2026

Evaluation of the use of segmentation-based and deconvolution-based three-dimensional joint space width analysis of the hand and wrist.

Jilmen Quintiens, Tadiwa H Waungana, Michael T Kuczynski, Sarah L Manske, G Harry van Lenthe

Abstract read
In one paragraph

Article in JBMR plus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jilmen QuintiensBiomechanics Section, Department of Mechanical Engineering, KU Leuven, 3001 Leuven, Belgium.ORCID https://orcid.org/0000-0003-2007-9329
Tadiwa H WaunganaMcCaig Institute for Bone and Joint Health, University of Calgary, Calgary, AB T2N4Z6,  Canada.ORCID https://orcid.org/0000-0002-0430-4242
Michael T KuczynskiMcCaig Institute for Bone and Joint Health, University of Calgary, Calgary, AB T2N4Z6,  Canada.ORCID https://orcid.org/0000-0001-5671-1205
Sarah L ManskeMcCaig Institute for Bone and Joint Health, University of Calgary, Calgary, AB T2N4Z6,  Canada.ORCID https://orcid.org/0000-0003-0888-9556
G Harry van LentheBiomechanics Section, Department of Mechanical Engineering, KU Leuven, 3001 Leuven, Belgium.ORCID https://orcid.org/0000-0001-8303-4959

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Three-dimensional morphometric analyses of joint space from CT scans can provide a quantitative and unbiased evaluation of radiographic damage from arthritis. This potentially offers greater sensitivity for disease assessment and monitoring than traditional ordinal scoring systems. Previously established methods for 3-dimensional joint space analysis from CT scans can be categorized into segmentation-based and grayscale deconvolution-based methods. However, segmentation-based methods have not been employed for joints other than metacarpophalangeal joints, nor have they been compared to deconvolution-based methods. This study compared the joint space width (JSW) distribution from various hand and wrist joints in photon-counting CT images, using both measurement approaches. From these distributions, the mean (JSW.Mean), standard deviation (JSW.SD), maximum (JSW.Max), minimum (JSW.Min), 95th percentile (JSW.95%), and fifth percentile (JSW.5%) values were calculated. For each morphometry parameter, agreement between the 2 methods was assessed by calculating the coefficient of determination (R

Indexed as

joint space widthosteoarthritisphoton-counting CTrheumatoid arthritisSPECTRA

Identifiers

PMID42110974
PMCPMC13156491

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.